1;Preface;5 2;Content;9 3;List of Contributors;17 4;Abbreviations;19 5;Chapter 1 Monitoring of Intracranial Pressure (ICP): A Review;21 5.1;1.1 Normal Intracranial Pressure Values;22 5.2;1.2 Regional Differences in Intracranial Pressure;22 5.3;1.3 Pressure/Volume Relationship;23 5.4;1.4 Pressure Waves;24 5.5;1.5 Critical Levels of Intracranial Pressure;25 5.6;1.6 Intracranial Pressure: Impact on Mortality;27 5.7;1.7 Intracranial Pressure After Intracranial Surgery;27 5.8;1.8 Approaches to Control of Intracranial Hypertension;27 5.9;1.9 Control of Cerebral Blood Volume and Intracranial Pressure;28 5.10;1.10 Positive End-Expiratory Pressure and Continuous Positive Airway Pressure;31 5.11;1.11 Dihydroergotamine (DHE);32 5.12;1.12 The Lund Model;33 5.13;1.13 Hyperventilation (HV);33 5.14;1.14 Indomethacin ;39 5.15;1.15 Metabolic Control of Cerebral Blood Flow;41 5.16;1.16 Analgesics ;46 5.17;1.17 Muscular Relaxation;46 5.18;1.18 Osmotic-Acting Drugs, Plasma Expanders and Diuretics;47 5.19;1.19 Mannitol ;48 5.20;1.20 Glycerol;53 5.21;1.21 Hypertonic Saline ;53 5.22;1.22 Furosemide;55 5.23;1.23 Corticosteroids;56 5.24;References;57 6;Chapter 2 Material Included in the Database;79 6.1;2.1 Diagnosis of Tumour, Localization of Cerebral Aneurysm and Hunt and Hess Gradation;80 6.2;2.2 Anaesthesia;81 6.3;2.3 Intracranial Pressure-Reducing Procedures;84 6.4;2.4 Discussion;84 6.5;References;86 7;Chapter 3 Method;87 7.1;3.1 Neuroradiological Examination in Patients with Cerebral Tumours;88 7.2;3.2 Localization of Aneurysm and Hunt and Hess Gradation;88 7.3;3.3 Anaesthesia and Monitoring;88 7.4;3.4 Fluid Administration and Regulation of Blood Pressure;90 7.5;3.5 Subdural Intracranial Pressure and Cerebral Perfusion Pressure;90 7.6;3.6 Catheterization of the Internal Jugular Vein and Blood Gas Analyses;91 7.7;3.7 Measurement of Cerebral Blood Flow and Cerebral Metabolic Rate of Oxygen;91 7.8;3.8 Measurement of Flow Velocity;92 7.9;3.9 Effect of Hyperventilation and Indomethacin;92 7.10;3.10 Estimation of Dural Tension and Cerebral Swelling;92 7.11;3.11 Measurement of Intracranial Pressure During Tilting of the Operating Table;92 7.12;3.12 Comparative Studies of Intracranial Pressure-Reducing Methods;93 7.13;3.13 Studies of the Effect of Central Analgetics in Patients with Cerebral Tumours;94 7.14;3.14 Studies of Propofol Bolus Dose;94 7.15;3.15 Patients Subjected to Controlled Studies;95 7.16;3.16 Statistical Analysis;95 7.17;References;95 8;Chapter 4 Comparative Studies of Intracranial Pressure in Patients With and Without Space- Occupying Lesions;97 9;Chapter 5 Studies of Regional Subdural Pressure Gradients During Craniotomy;109 9.1;Study 1: Studies of Pressure Gradients Between Subdural Intracranial Pressure and Pressures Within the Neuroaxis, Including Intraventricular Pressure and Lumbar Spinal Pressure;111 9.2;Study 2: Subdural Intracranial Pressure Gradients Within the Supratentorial Surgical Field;113 9.3;Study 3: Subdural Intracranial Pressure Gradients Within the Surgical Field in Infratentorial Surgery;115 9.4;Study 4: Changes in Subdural Intracranial Pressure During Opening of Dura;117 9.5;Discussion;117 9.6;References;121 10;Chapter 6 Subdural Intracranial Pressure and Degree of Swelling After Opening of Dura in Patients with Supratentorial Tumours;123 10.1;Study 1: Subdural Monitoring of ICP During Craniotomy: Thresholds of Cerebral Swelling/Herniation;124 10.2;Study 2: Craniotomy for Supratentorial Brain Tumours: Risk Factors for Brain Swelling After Opening of Dura Mater;127 10.3;Discussion;131 10.4;References;134 11;Chapter 7 Subdural Intracranial Pressure, Cerebral Haemodynamics, Dural Tension and Degree of Swelling After Opening of Dura in Patients with Infratentorial Tumours;135 11.1;Study 1: The Relationship Between Intracranial Pressure and the Degree of Brain Swelling in Patients Subjected to Infratentorial Surgery;136 11.2;Study 2: Patients Subjected to Craniotomy for Occipital Tumours with Special Reference to Positio