The diagnosis of myelodysplastic syndromes (MDS), a heterogeneous group of clonal hematopoietic disorders, is being made with increasing frequency over the past decade owing to increased recognition, improved understanding, and an aging population. This book, completely updated since the first edition, summarizes in a concise and focused way the current knowledge of all aspects of MDS. Clinical presentation, etiology, epidemiology, molecular biology, classification, and staging are all discussed. Clear guidance is provided on diagnosis and differential diagnosis, and treatment strategies are explained in detail, including administration of hematopoietic growth factors, biologically based treatment, hematopoietic stem cell transplantation, and supportive care. Additional chapter is devoted to MDS in children. This practically oriented book will be of value to a broad spectrum of students and practitioners in the field.

Clincial Presentation and Differential Diagnosis

Epidemiology and Etiology
Cytogenetic Diagnosis of Myelodysplastic Syndromes
MDS Stem Cell Biology
The Biology of Myelodysplastic Syndrome Associated with Isolated del(5q)
Other
Overlap with MPN
Classification and Staging of Myelodysplastic Syndromes
Immunophenotyping in Myelodysplastic Syndrome
Prognostic Models for Patients with Myelodysplastic Syndromes
Low Risk MDS
Management of High-Risk Myelodysplastic Syndrome
Hematopoietic Cell Transplantation
MDS in Children.