Nearly 25 years of intensive research have uncovered many diverse functions for the dimeric transcription factor known as NF-kappaB (nuclear factor-kappaB). NF-kappaB affects most aspects of cellular physiology-from immunity and inflammation to apoptosis, cell survival, growth, and proliferation

Preface

Understanding the Logic of IkappaB:NF-kappaB Regulation in Structural Terms
IKK regulation and human genetics
Specialized chromatin patterns in the control of inflammatory gene expression
Macrophages and NF-kappaB in Cancer
NF- B/Rel proteins and the humoral immune responses of Drosophila melanogaster
IKK and NF-kappaB mediated functions in carcinogenesis
Control of NF-kappaB activity by proteolysis
NF-kappaB as a target for oncogenic viruses
NF-kappaB and Innate Immunity
Inhibition of NF-kappaB signaling as a strategy in disease therapy
NF- B and mucosal homeostasis
NF-kappaB In liver cancer - the plot thickens
Subject index.