Natural killer (NK) cells have been at the forefront of immunology for two decades. During that time, a great amount of information about these cells has been obtained. They are important in antiinfectious and antitumoral defense and shape the adaptive immune response. In addition, they can act as immunoregulatory cells. In recent years, the therapeutic potential of NK cells in cancer immunotherapy has become increasingly evident. This book describes in detail current knowledge about NK cells and covers a broad range of NK cell-related topics, including those that are not frequently reviewed, e.g. NK cells and allergy or NK cells and skin diseases.

Natural Killer Cells: Deciphering Their Role, Diversity and Functions

Dissecting Human NK Cell Development and Differentiation
Diversity of KIR Genes, Alleles and Haplotypes
NK Cell Education and CIS Interaction Between Inhibitory NK Cell Receptors and Their Ligands
Trogocytosis and NK Cells in Mouse and Man
Virus Interactions with NK Cell Receptors
The Role of NK Cells in Bacterial Infections
NK Cells and Autoimmunity
NK Cells and Allergy
Natural Killer Cells and Their Role in Hematopoietic Stem Cell Transplantation
NK Cells, NKT Cells, and KIR in Solid Organ Transplantation
NK Cells in Autoimmune and Inflammatory Diseases
Natural Killer Cells and the Skin
NK Cells in Oncology
The Role of KIR in Disease
Interactions Between NK Cells and Dendritic Cells
Modulation of T Cell-Mediated Immune Responses by Natural Killer Cells
Interactions Between NK Cells and Regulatory T Cells
Interactions Between B Lymphocytes and NK Cells: An Update
The RegulatoryNatural Killer Cells
NK Cells and Microarrays
Natural Killer Cells in the Treatment of Human Cancer.