Natural Killer Cells
At the Forefront of Modern Immunology
Natural killer (NK) cells have been at the forefront of immunology for two decades. During that time, a great amount of information about these cells has been obtained. They are important in antiinfectious and antitumoral defense and shape the adaptive immune response. In addition, they can act as immunoregulatory cells. In recent years, the therapeutic potential of NK cells in cancer immunotherapy has become increasingly evident. This book describes in detail current knowledge about NK cells and covers a broad range of NK cell-related topics, including those that are not frequently reviewed, e.g. NK cells and allergy or NK cells and skin diseases.
1;Preface;5 2;Contents;6 3;Natural Killer Cells: Deciphering Their Role, Diversity and Functions;9 4;Dissecting Human NK Cell Development and Differentiation;47 5;Diversity of KIR Genes, Alleles and Haplotypes;70 6;NK Cell Education and CIS Interaction Between Inhibitory NK Cell Receptors and Their Ligands;99 7;Trogocytosis and NK Cells in Mouse and Man;115 8;Virus Interactions with NK Cell Receptors;130 9;The Role of NK Cells in Bacterial Infections;158 10;NK Cells and Autoimmunity;181 11;NK Cells and Allergy;195 12;Natural Killer Cells and Their Role in Hematopoietic Stem Cell Transplantation;203 13;NK Cells, NKT Cells, and KIR in Solid Organ Transplantation;224 14;NK Cells in Autoimmune and Inflammatory Diseases;243 15;Natural Killer Cells and the Skin;257 16;NK Cells in Oncology;269 17;The Role of KIR in Disease;277 18;Interactions Between NK Cells and Dendritic Cells;301 19;Modulation of T Cell-Mediated Immune Responses by Natural Killer Cells;316 20;Interactions Between NK Cells and Regulatory T Cells;329 21;Interactions Between B Lymphocytes and NK Cells: An Update;344 22;The Regulatory Natural Killer Cells;368 23;NK Cells and Microarrays;389 24;Natural Killer Cells in the Treatment of Human Cancer;403 25;Index;420
Zimmer, Jacques
| ISBN | 9783642023095 |
|---|---|
| Artikelnummer | 9783642023095 |
| Medientyp | E-Book - PDF |
| Auflage | 2. Aufl. |
| Copyrightjahr | 2010 |
| Verlag | Springer-Verlag |
| Umfang | 428 Seiten |
| Sprache | Englisch |
| Kopierschutz | Digitales Wasserzeichen |
