Negative Co-Receptors and Ligands

Negative Co-Receptors and Ligands

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Adaptive immune responses serve as a key defense mechanism for the control of infections in vertebrates. Immune responses must be of sufficient strength to contain invading pathogens, antigen specific responses require regulatory mechanisms to ensure termination or downmodulation to avoid excessive damage to the host tissue. For both branches of the adaptive immune system, regulatory molecules i.e. coreceptors and ligands have been identified that control the signaling cascades initiated by engagement of the T cell and B cell antigen receptors. This book describes biological functions as well as molecular mechanisms of these molecules.
ISBN 978-3-642-26777-2
Artikelnummer 9783642267772
Medientyp Buch
Auflage Repr. d. Ausg. v. 2011
Copyrightjahr 2013
Verlag Springer, Berlin
Umfang VIII, 152 Seiten
Abbildungen VIII, 152 p.
Sprache Englisch