In this book, experts in the field provide comprehensive descriptions of the neuroanatomy of the hypothalamic neuroendocrine systems.

The book begins with an extensive discussion on the structural components of the neuroendocrine systems. The reader will be introduced to the anatomy and biology of the hypothalamus and the pituitary. The human hypothalamus is presented in particular detail using state-of-the-art imaging techniques.  In the next section, the neuroanatomy of traditional hypothalamo-hypophyseal systems is highlighted, with chapters describing magnocellular neuroendocrine cells and discussing the respective types of hypothalamic neurons that regulate various pituitary hormones.  Following this detailed structural and anatomical description of the neuroendocrine system, the book'sfinal section focuses on the hypothalamic control of neuroendocrine functions. This includes the control of circadian rhythm, metabolism and appetite via specific peptidergic circuits.

This book provides essential information on the neuroanatomy and control of neuroendocrine systems, addresses cutting-edge research questions posed by recent advances in the development of potent neuroanatomical tools, and highlights the latest technologies used in neuroendocrinology research, making it a valuable reference guide for students, trainees and established researchers alike. 

This is the twelfth volume in the International Neuroendocrine Federation (INF) Masterclass in Neuroendocrinology series, which aimsto illustrate the highest standards and to encourage the use of the latest technologies in basic and clinical research and hopes to provide inspiration for further exploration into the exciting field of neuroendocrinology.

Chapter 12 is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com

PART I. Structural Components of the Neuroendocrine Systems

Chapter 1. Ontogenesis of Hypothalamic Neurons in Mammals
Chapter 2. Advances in MRI-Based Anatomy of the Human Hypothalamus and Effects of the Hypothalamic Neuropeptide Oxytocin on Brain BOLD Signals
Chapter 3. Generation of Hypothalamus and Adenohypophysis from Human Pluripotent Stem Cells
Chapter 4. The Neurohypophysis and Urophysis - Ancient Piscine Neurovascular Interfaces
Chapter 5. Cytoskeletal Organization and Plasticity in Magnocellular Neurons
PART II. Neuroanatomy of Hypothalamo-hypophyseal Systems
Chapter 6. Neuroanatomical and Functional Relationship Between Parvocellular and Magnocellular Oxytocin and Vasopressin Neurons
Chapter 7. Fine Chemo-Anatomy of Hypothalamic Magnocellular Vasopressinergic System with an Emphasis on Ascending Connections for Behavioural Adaptation
Chapter 8. Neuroanatomy of the GnRH/Kisspeptin System
Chapter 9. Corticotropin-Releasing Hormone inthe Paraventricular Nucleus of the Hypothalamus- Beyond Hypothalamic-Pituitary-Adrenal Axis Control
Chapter 10. Multifactorial Regulation of the Activity of Hypophysiotropic Thyrotropin-Releasing Hormone Neurons
PART III. Hypothalamic Control of Neuroendocrine Functions
Chapter 11. Circadian Control of Neuroendocrine Systems
Chapter 12. The Neuroanatomical Organization of Hypothalamic Feeding Circuits
Chapter 13. Melanin-Concentrating Hormone, Neuropeptide E-I, and MCH Receptor 1
Chapter 14. Neuroanatomy of Tuberoinfundibular Peptide 39 Related to Neuroendocrine and Behavioral Regulations
Chapter 15. Functional Chemoanatomy of PACAP in Neuroendocrine and Neuronal Circuits
Chapter 16. Functional Neuroanatomy of Relaxin-3/RXFP3 Systems in the Brain: Implications for Integrated Neuroendocrine and Behavioural Control.