These eight volumes, which developed out of the international congress "Update and Future Trends in Fibrin Sealing in Surgical and Nonsurgical Fields" held in November 1992, present the state of the art in fibrin sealing. In itially, fibrin sealant played an important role in surgery. During the past few years, it has been increasingly applied nonsurgically, and we can now say that it has become an integral component of medical treatment. The doubts which have been raised by nonusers about the efficacy of fibrin sealant are no longer valid. The correct indication and technique continue to be basic prerequisites for effective treatment. Even today - 20 years after fibrin sealant was first used - the three most prominent effects of fibrin sealant are still hemostasis, sealing of the wound, and support of wound healing. The problems posed by the transmission of viral infections have gained sub stantially in importance because of the potential transmission of AIDS via fi brin sealant. Fortunately, this is so unlikely today that it no longer represents a cause for concern, which does not mean, however, that research in this field can be discontinued.

I. Neurosurgery

Our Experience with Human Fibrin Glue in Neurosurgical Procedures
New Trends in Enlarged Middle Cranial Fossa Surgery
Prevention and Treatment of Cerebrospinal Fluid Rhinorrhea Following Transsphenoidal Surgery on Pituitary Gland Adenomas
Preoperative Tumor Embolization with Fibrin Glue: Indications and Results
Preliminary Observations of Local Therapy with Interferon-? with Use of Fibrin Glue as a Carrier in Malignant Cerebral Tumor
Frontobasal and Orbital Reconstruction Using Biological Material
Fibrin Sealing in Spinal Neurosurgery
Neurosurgical Reconstruction of Obstetric Brachial Plexus Lesions with the Use of Fibrin Sealing
Centrocentral Anastomosis: An Elegant Alternative in the Surgical Treatment of Painful Amputation Neuromas
II. Ophthalmic Surgery
Fibrin Sealant in Ophthalmic Plastic and Reconstructive Surgery
Progress in Fibrin Sealing of Eye Lens and Conjunctiva
Morphological Reactions Following Fibrin Retinopexy in Rabbit Eyes
Fibrin Adhesive for Wound Closure in Small-Incision Cataract Surgery
Wound Closure with Fibrin Adhesive in Cataract Surgery
III. ENT
Rhinologic Applications of Fibrin Glue
Spray Application of Fibrin Glue in Microsurgical Ethmoidectomy - Technique and Short-Term Results
Use of Fibrin Glue in Craniofacial and Skull Base Trauma
Use of Fibrin Glue in Rhinoplasty
Use of Fibrin Glue in Intracranial Procedures Following Acoustic Neuroma Surgery: Application in Facial Nerve Reconstruction and Prevention of Cerebrospinal Fluid Rhinorrhea
Partial and Total Reconstruction of the Auricle
Mastoid Cavity Filling for Bone Reconstruction with a Mixture of Fibrin Glue and Ceramic Granules
Fibrin Sealing in Tympanoplasty
Compound Prosthesis and Cartilage Layer: Two New Applicationsof Fibrin Sealing in Reconstructive Middle Ear Surgery
Use of Bovine Heterologous Cartilage and Fibrin Sealant in Middle Ear Reconstructive Surgery
Pharyngeal Fistulas Following Total Laryngectomy Treated with Dilatation and Fibrin Sealant
Minimally Invasive Surgery with a New Distending Diverticuloscope and Use of Fibrin Sealing for Endoscopic Laser Dissection of Zenker's Diverticulum
Fibrin Sealing in Endolaryngeal Surgery
Use of Tissucol in Laryngology and in Head and Neck Surgery.