This book adopts a multidisciplinary approach to examine in detail a range of interesting new concepts in the diagnosis and therapy of pancreatic adenocarcinoma. It is divided into three parts. The first part provides an epidemiological and clinical overview of the disease, followed by an update on pathological findings, including new discoveries in the area of molecular biology. The second part, on diagnosis, offers detailed and comprehensive information on the advantages and disadvantages of different imaging techniques, including nuclear medicine and endoscopic ultrasound. The concluding part gives a panoramic overview of the various therapeutic options, from surgery to chemotherapy and palliative approaches based on interventional endoscopy and radiology. This book will be a valuable source of information for clinicians involved in the management of pancreatic adenocarcinoma and for all who are interested in updating their knowledge of the disease, including fellows and senior residents.

Part I: Epidemiology, Clinical Aspects and Pathology: Epidemiology, Risk Factors and Clinical Presentation

Pathology and Molecular Biology
Part II: Diagnosis: The Case for US.-The Case for MDCT
The Case for MRI.-EUS: When and Why
Pre-Operative Laparoscopy: Is it Still Necessary?
The Role of PET-CT in Diagnosis, Staging and Follow-Up
A Cost Decision Analysis for Diagnosis and Staging
Part III: Therapy: The Case for Surgery
The Locally Advanced Non-Metastatic Cancer
The Metastatic Patient: Adjuvant Therapy
The Role of Interventional Endoscopy
The Role of Interventional Radiology
Subject Index
List of Contributors.