This book gathers selected, extended and revised contributions to the 15^th International Symposium on Computer Methods in Biomechanics and Biomedical Engineering (CMBBE2018), and the 3^rd Conference on Imaging and Visualization, which took place on 26-29 March, 2018, in Lisbon, Portugal. The respective chapters highlight cutting-edge methods, e.g. new algorithms, image analysis techniques, and multibody modeling methods; and new findings obtained by applying them in biological and/or medical contexts. Original numerical studies, Monte Carlo simulations, FEM analyses and reaction-diffusion models are described in detail, together with intriguing new applications.

The book offers a timely source of information for biologists, engineers, applied mathematicians and clinical researchers working on multidisciplinary projects, and is also intended to foster closer collaboration between these groups.

Chapter 1. The impact of patches on blood flow disorders in carotid artery

Chapter 2. Numerical study of carotid bifurcation angle effect on blood flow disorders
Chapter 3. Evaluating the effect of tissue anisotropy on brain tumor growth using a mechanically-coupled reaction-diffusion model
Chapter 4. Prediction of stress and strain patterns from load rearrangement in human osteoarthritic femur head: finite element study with the integration of muscular forces and friction contact
Chapter 5. Numerical simulation of the deployment process of a new stent produced by ultrasonic-microcasting: the role of the balloon's constitutive modeling
Chapter 6. New techniques for combined FEM-multibody anatomical simulation
Chapter 7. Computational cell-based modelling and visualization of cancer development and progression
Chapter 8. Estimation of 6 degree of freedom accelerations from head impact telemetry system outputs for computational modeling
Chapter 9. Physiological Cybernetics: methods and applications
Chapter 10. New computational solution to compute the uptake index from ^99mTc-MDP bone scintigraphy images.