From the first to the third of August, 1980, an international sym posium entitled "New Trends in Allergy" was held in Munich, sponsored by the Ludwig-Maximilian University, Munich, in cooperation with the German Society for Allergy and Immunity Research and the European Society for Dermatological Research. The symposium pursued two main goals: to bring allergy oriented colleagues from various specialties such as dermatology, otorhinolaryngology, pediatrics, internal medicine, immunology, and pulmonology together for interdisciplinary contacts and dis cussions; and to attract internationally known experts in an effort to disseminate information on new and fundamental develop ments in allergology. The fact that English has become the lingua franca at congresses for the exchange of ideas in medical specialties led to the decision to hold the symposium in English. In spite of the mild handicap this posed for some participants, it was also a major factor in the symposium's success. This book contains the papers delivered by the invited speakers together with the poster presentations. They cover both basic ex perimental research as well as clinical problems in allergology.

The Mast Cell

The Mast Cell: Morphology and Ontogeny
Mast Cell Activation and Secretion
Mast Cell Granule Induced Late Phase Responses (LPR) in Rat Skin: Effect of Corticosteroids (CCS). Partial Purification of Infiltration Inducing Factors
The IgE Receptor
Releasability - a New Dimension in Basophil and Mast Cell Reactivity
In Vitro Sensitization of Rat Mast Cells by Human Serum IgE Tested by Histamine Release
Stress and Histamine
Vasoactive Mediators
Release of Proinflammatory Peptides by Complement in Prophyrin-induced Photosensitivity
Interaction of DNA with the Early Components of Complement
Pharmacological Regulation of Histamine Release in Skin
Kallikreins, Kinins and Allergy
Induction of Late Cutaneous Reactions (LCR) by Skin Blister Fluid (SBF) from Allergen-Tested and Normal Skin
Kallikrein Activity in Skin Blister Fluid from Allergen-induced Dual Skin Reactions
Diagnostics
Variations of the Radioallergosorbent Test for Measurement of IgE Antibody Levels, Allergens and Blocking Antibody Activity
Drug Influences upon Skin Test Reactivity
Immunological Work up
Immunohistologic Diagnosis with Protein A - Peroxidase in Allergic Vasculitis
Thermographic Analysis of Skin Test Reactions by AGA Thermovision and Ikotherm (Zeiss)
Relationship Between Skin Tests, Bronchial Provocation and RAST in Patients with Bronchial Asthma
Skin Tests and Dermatophagoides Allergy
Comparison Between Radioimmunoassay (RIA) and Enzyme Immunoassay (EIA) for the Determination of Serum Total IgE and IgE Antibodies
Clinical Allergy
Allergic Vasculitis
Urticarial Vasculitis
Photoallergy
Localization of a Clinically Relevant Antigenic Determinant Within an Insect Hemoglobin (Erythrocruorin) of Chironomus (Sequence 58-98 of CTT VI).-Specific Serum Factors Mediate Responses to Pollen
Risk-Factors for the Development of Pollinosis and Extrinsic Asthma
Ragweed Pollen Allergy in Austria
Allergy Caused by Internal Exposure to Copper (Copper-T-IUD)
Contact Dermatitis
Langerhans Cells in Contact Hypersensitivity
Vasoactive Mediators in Contact Sensitivity
Topography of Contact Dermatitis and Patch Testing
The E.S.S. - Excited Skin Syndrome (Alias the "Angry Back")
Atopic Dermatitis
Histamine Release in Atopic Dermatitis of Childhood
T Cell Defects in Atopic Dermatitis: Therapeutic Consequences
Atopic Dermatitis: a Disease of Immuno-vegetative (Autonomic) Dysregulation
Lymphocyte Function in Atopy: Regulatory Role of Beta-adrenergic Receptors
Spontaneous Tritiated Thymidine Incorporation by Cells of the Dermal Infiltrate and by Peripheral Blood Lymphocytes in Atopic Dermatitis
Ascaris Suum Extract: Polyclonal Activator Properties as Possible Tools for Investigating in Vitro IgE Production in Humans
Clinical Therapy
Evaluation and Treatment of Insect Sting Allergy
Insect Venom Tolerance: IgG "Blocking" Antibodies and Sting Provocation
Clinical Aspects and Therapy of Hereditary Angioneurotic Edema
Modern Approaches to Treatment of Chronic Urticaria
ALG Therapy in Horse IgG Sensitized Kidney Transplanted Patients
Hapten Inhibition of Dextran-induced Anaphylactoid Reactions: a Clinical Study
New Therapeutic Concepts (Experimental Studies)
Regulation of IgE Response by Antiidiotypes and Adjuvants
Suppression of IgE Antibodies with Tolerogenic Derivatives of Allergens
Specific IgE Anti-Timothy Immunosuppression by P4 Allergen Coupled to Poly (N-Vinylpyrrolidone)
Recent Studies with Human IgE Pentapeptide (HEPP)
Decrease of Circulating Antibodiesin Blood by Enteral Antigen Application
Epilogue
Allergic, but to what?
Index of Authors.