To give an update in the field of haemostasis scientists andclinicians fromoverseas and European countries met to dis-cuss the new trends in pathophysiology and clinical impli-cations. This book is devoted to the interactions of endo-thelial functions, tissue factors, coagulation inhibitorsand haemostasis as well as detection and prophylaxis ofthromboembolism. Data are presented of significant new re-search work on molecular and clinical approaches to diseasesin haemostasis.

Endothelial Functions and Haemostasis

Structure, Shape and Function of Glycosaminoglycans
Structure and Metabolism of Glycosaminoglycans
Fibrin Polymerization and Its Role in Regulating Haemostasis
Function of von Willebrand Factor in Plasma
Biosynthesis and Assembly of the Factor VIII - von Willebrand Factor Complex
Modulation of Endothelial Cell Function by Hypoxia: Perturbation of Barrier and Anticoagulant Function and Induction of a Novel Procoagulant Activity
Tissue Factors and Endothelium
Platelet Adhesion; A Concerted Action of Hemodynamic and Biochemical Processes
Modulation of Endothelial Functions by Advanced Glycosylation End Products
Procogulant Activities of Leukocytes
Cytokine Induced Stimulation of Endothelial Cells in Vitro
Anti-Platelet Treatment of Metastasis
The Molecular Anatomy of Vitronectin as Extracellular Regulator Protein: Multifunctional Properties of the Heparin-Binding Domain
Mode of Action of Annexin V (Vascular Anticoagulant Alpha), A Protein Synthesized by the Vessel Wall
Coagulation Inhibitors and Haemostasis
Clinical Pharmacologal Profile of Low Molecular Weight Heparins
Anticoagulant Actions of Sulphated Polysaccharides
Development of Synthetic Proteinase Inhibitors as Anticoagulant Agents
Antithrombin and Its Deficiency States
"New" Coagulation Inhibitors
Biological Function of Vitamin K Antagonists
Plasminogen Activator Inhibitors: Biological Effects
Fibrin-Specific Clot Lysis with Single Chain Urokinase-Type Plasminogen Activator (scu-PA)
Antibody - Mediated Thrombolysis: Promise and Problems
Thromboembolism: Detection and Prophylaxis
Causation and Prevention of Coronary Thrombosis: Present Situation
Non-Invasiva Diagnostic Techniques in Deep Vein Thrombosis
Evaluationof the Bleeding Effects of Antithrombotic Drugs
List of Participants
List of Sponsors.