Now in its second edition, this comprehensive handbook provides a state-of-the-art overview of recent advances in drug and non-drug therapies for obesity and diabetes. It also addresses major comorbidities, covering topics such as, cardiovascular diseases, renal and neuropsychiatric disorders, appetite control and micro RNAs. Special attention is also devoted to pediatric care, including the latest recommendations for therapy and prevention. 

Obesity and type 2 diabetes are among the top global health-care budget concerns worldwide and impact professional practice at all levels: in hospitals, clinics and physicians' offices alike. They prominently feature in headlines, and virtually no family, community or country is exempt from their protean, deleterious consequences. Furthermore, given the multiple intersections in their pathways, they often go hand in hand.

The good news is that scientific advances in all fields, including genomics, metabolomics, lipidomics and microbiomics, are increasing our understanding of these two disease areas. At the same time, artificial intelligence, machine learning, mobile health and advanced implantable and external devices are rendering prevention and management more available, safe and cost-effective. In addition, bariatric and metabolic surgery has evolved from a niche specialty to an officially endorsed option for several modalities of obesity and diabetes.

This book presents the latest lifestyle, pharmacological, surgical and non-surgical treatment options, including endoscopic intervention and cell therapy. Objectively reviewing natural and artificial sweeteners and critically examining issues such as public health initiatives, government mandated taxes for unhealthy foods and environmental planning, no stone is left unturned in gathering the latest practical information. As such, the book will appeal to seasoned specialists, as well as students and healthcare professionals in training.

Introduction to Obesity and Diabetes- The windows of opportunity

Nutrition transition and obesity trends in Argentina within the Latin American context
Challenges and Economic Burden of Diabetes in Africa
Brown adipose tissue in obesity and diabetes
White and Brown Adipose Tissue in Obesity and Diabetes
microRNAs in obesity and metabolic diseases
From Adipogenic Viruses to Anti-Diabetic Drug: A Translational Journey
Genetic profiles in the obese population
The Upstream Environment for the Obesity Epidemic
Inflammation and its role in obesity-related complications
Cross talk between adipose tissue, macrophages and other immune cells: Development of obesity and inflammation-induced metabolic diseases
Diabetes forecasts and statistics for the coming decades
Pancreatic islets of Langerhans: adapting cell and molecular biology to changes of metabolism
Targeting advanced glycation end products (esRAGE and sRAGE) for obesity, diabetes and its associated complications
Anti-incretin effect: a missing link between obesity, diabetes and metabolic surgery
An update on Mendelian forms of obesity and their personalized treatments
The Genetic Basis of Diabetic Kidney Disease
Epigenetics and chronic inflammation: Role in early detection of type 2 diabetes
Salivary and Urinary Metabolome in Pediatric Obesity and Metabolic Syndrome
State-of-the-Art Metabolomics Investigations of Type 2 Diabetes
The gut microbiome and type 2 diabetes mellitus
Immunotherapeutic Approach to the Treatment and Prevention of Obesity
Metabolic Syndrome Update
Non-alcoholic fatty liver disease: a global public health issue
Non-Alcoholic Fatty Pancreatic Disease (NAFPD)
Normal weight obesity - A hidden pandemic
Obesity in Children/Adolescents and Obesity-Related Comorbidities
Obesity and cancer: linked molecular mechanisms
Cognitive impairment in obesity and diabetes
Metabolic pathways underlying neuropsychiatric disorders and obesity
Heart failure and the obesity paradox
Inflammatory mechanisms in diabetic kidney disease
The epidemiology of the diabetes - depression comorbidity in Brazil -inequality and interaction
Contribution of Hyperglycemia and Unhealthy Diet to Cardiovascular Mortality
Gestational Diabetes Mellitus
Update on Gestational Diabetes
Vascular complications in type 2 diabetes
What We Know and Don't about High-Intensity Sweeteners
Personalised Molecular Feedback for Weight Loss
Diabetes and Obesity in the Child and Adolescent: Guidelines and Challenges
Type 2 diabetes - an unresolved disease
Glucose control in the ICU
Continuous glucose monitors as wearable lifestyle behavior change tools in obesity and diabetes
Endoscopic techniques for obesity and diabetes
Bariatric embolization: a possible non-surgical option for weight reduction
Progress in noninvasive beta-cell mass imaging
Cancer staging with 18F-FDG PET/CT in hyperglycemic patients
Pancreatic Islet Transplantation: A Surgical Approach to Type 1 Diabetes Treatment
Pancreatic Transplantation in Diabetes: Indications, Contraindications and Perspectives. -Pharmacotherapy of Type 2 Diabetes
GLP1-Receptor Agonists in Diabetes: Drugs, General Effects, and Cardiovascular Impact
Diabetes and treatments
Treatment of Diabetes and Heart Failure
Cardiovascular impact of newer diabetes medications
Pathogenesis and Molecular Targets in treatment of Diabetic Wounds
Efficiency in public health through the promotion of Diabetes Day Hospitals: a regional proposal
Surgical options in obesity and diabetes
One anastomosis gastric bypass in the treatment of obesity: effects on body weight and the metabolome
Robotic bariatric surgery
The Role of Obesity and Bariatric Surgery in the Management of Knee and Hip Osteoarthritis
Relapse of diabetes after metabolic/bariatric surgery
Malnutrition in Obesity
Sugar-Sweetened Beverage Taxes: Origins, Mechanisms, and Current Worldwide Status
Mobile Health Interventions for Weight Management in Overweight and Obese Populations
Biomarkers and Machine Learning Applications in Obesity
Current approaches in diabetes mellitus prediction: applications of machine learning and emerging biomarkers
Polycystic ovary syndrome and sarcopenic obesity
Drug Pipeline for Obesity Therapy
MC4R as a Target for Pharmacotherapeutic Treatment of Obesity and Type-2 diabetes
Nanotechnology: Can it be a crusader in diabesity?
Old and new anti-obesity devices for medical, surgical, and endoscopical use
Electroceutical approaches for gastroparesis
Useful Online Resources Hosting Information on Obesity and Diabetes.