Our goal for this second edition of Oncologic Therapies is to again provide a brief introduction to the principles and practice of oncology and to oncologic therapies. The book provides a - scription of the major treatment modalities including surgery, radiation therapy, and systemic therapies including classic chemotherapy and biological therapies as well as a brief ov- view of supportive care and quality of life assessments. This is followed by a discussion of site-specific cancers covering the hematologic malignancies and solid tumors. Each chapter is designed to provide a brief discussion of background infor- tion including epidemiology,risk factors,and staging principles followed by a description of standard therapies according to stage as well as current investigational approaches. While the major pathological and clinical features of each disease are d- cussed,the emphasis of this book is clearly on the state of the art of standard and investigational therapies for each tumor type. As such,this book should be useful to general internists with an interest in oncology as well as housestaff and junior oncologists of all major oncologic modalities seeking a brief and focused patient management resource. References providing more - depth discussion for each field are also provided. We rec- mend that any information pertaining to specific chemotherapy regimens and dosing be confirmed in a primary reference since we cannot exclude the possibility of an occasional typograp- cal error.

1 Principles of Surgical Oncology

2 Principles of Radiation Oncology*euticModalities
3 Principles of Cancer Chemotherapy
4 Principles of Cancer Chemoprevention
5 Principles of Cancer Immunotherapy
6 Ethics and the Development of New Oncologic Therapies:*Informed Consent, Equipoise, and the Randomized Trial
7 Diagnosis and Management of Oncologic Emergencies
8 Infectious Complications of Oncologic Therapy
9 Hematopoietic Growth Factors
10 Pain Management
11 Chemotherapy-Induced Nausea and Vomiting
12 Pleural Effusions
13 Measuring Quality of Life
14 Acute Leukemia
15 Chronic Myelogenous Leukemia
16 Chronic Lymphocytic Leukemia
17 Myelodysplastic Syndromes
18 Myeloproliferative Disorders
19 Hairy Cell Leukemia
20 Hodgkin's Lymphoma
21 Cutaneous T Cell Lymphomas
22 Non-Hodgkin's Lymphoma
23 Multiple Myeloma and Other Plasma Cell Dyscrasias
24 Early Breast Cancer
25 Locally Advanced, Locally Recurrent,*and Metastatic Breast Cancer
26 Head and Neck Tumors
27 Carcinoma ofthe Esophagus
28 Non-Small Cell Lung Cancer
29 Small Cell Lung Cancer
30 Mesothelioma
31 Colorectal Cancer
32 Anal Cancers
33 Gastric Cancer
34 Hepatobiliary Cancer, Pancreatic Cancer,*and Neuroendocrine Cancers of the Gastrointestinal Tract
35 Prostate Cancer
36 Testicular Cancer
37 Renal Cancer
38 Genitourinary Malignancies: Bladder/Penis/Urethral Cancers
39 Uterine Cancer
40 Cervical, Vulvar, and Vaginal Cancer
41 Ovarian Cancer
42 Primary and Metastatic Brain Tumors
43 Bone Sarcomas
44 Soft-Tissue Sarcomas
45 Thyroid Malignancies
46 Cutaneous Melanoma
47 Non-Melanoma Skin Neoplasms.