This book provides a comprehensive overview of oral signs of a broad spectrum of systemic diseases including gastrointestinal, hematologic, and endocrine, in addition to infectious, nutritional, autoimmune, genetic and connective tissue diseases. An overview of associated key signs and salient features to look for on oral exam is provided as well as other clinical manifestations, differential diagnoses, and treatment recommendations. The mouth is an important anatomical location with a role in many critical physiologic processes that are frequently involved in conditions that affect the skin or other organ systems. In many instances, oral manifestations of a disease precede the appearance of other stigmata. Therefore, early recognition of oral signs and symptoms associated with underlying systemic diseases can be invaluable to the clinician in establishing a diagnosis and prompt initiation of therapy. This book, written for dermatologists, dentists, otolaryngologists, and oral medicine specialists, offers a structured approach to the therapy and management of diseases affecting the oral mucosa.

Nasim Fazel Professor of Clinical Dermatology University of California, Davis Department of Dermatology Sacramento, CA USA

Nasim Fazel, MD, DDS, MAS, is an Associate Professor of Dermatology and a board certified dermatologist and dentist. In addition to general dermatology, Dr. Fazel has a special interest in the medical management of oral mucous membrane disease and soft tissue pathology. Her background in dentistry provides for insight into the pathophysiology and treatment of aphthous ulcers, burning mouth syndrome, oral lichen planus, and oral vesiculobullous disease (e.g., pemphigus and pemphigoid). Dr. Fazel is regarded as a leading expert in the field of Oral Medicine by many colleagues who refer these difficult and challenging conditions to her. Dr. Fazel is also Director of the newly established Graduate Medical Education Research Program in the Department of Dermatology. The program is dedicated to research involving all aspects of residency training and education. This includes areas such as residency evaluation and teaching methods, dermatology specific core competencies, resident career choices, residency candidate selection methods, and resident wellness.