This book provides state of the art knowledge on a broad range of clinical issues in pancreatic cancer, covering topics from screening and pathophysiology to surgical treatments. In particular, the focus is on current controversies and on evidence-based surgical techniques. Further aspects considered include the management of precancerous lesions, diagnostic methods, perioperative care and nonsurgical treatment. The description of surgical methods is supported by many helpful illustrations and important technical issues are carefully addressed. Determination of resectability and extent of surgery is also discussed. Based on recent developments in surgical techniques, some surgeons are performing more and more radical operations. It is essential, however, that surgical strategy is based on the best available evidence and surgeons will find that this book offers valuable help in achieving this aim. In addition, it will be a great asset in clinical practice for all who are involved or interested in the management of pancreatic cancer.

1. Pathology & Tumor biology

Epidemiology
Genetic background & hereditary pancreatic cancer
Pathological classification
Tumor biology (precancerous lesion and mode of spread)
Current update/controversial issue
Specimen handling & margin status
Tumor marker
2. Diagnosis
CT, MRI
Endoscopic diagnosis
PET
Current update/controversial issue
Functional imaging for pancreatic neoplasms (including PNET)
3. Treatment guideline
Staging and determination of resectability of pancreatic cancer
Guideline for the management of other pancreatic neoplasm
IPMN & MCN
SCN
pNET
Current update/controversial issue
Definition of borderline resectable PDAC
Role of neoadjuvant treatment
4. Surgery
Technical issues in surgery
Conventional Pancreatoduodenectomy
Vessel Resection for PDAC (type & technique)
Nerve plexus dissection
Organ preserving pancreatectomy
Type of Reconstruction
Isolated pancreatectomy
Mesenteric vessel first approach
DP-CAR
RAMPS
Minimal invasive pancreatectomy
Laparoscopic Pancreatoduodenectomy
Laparoscopic distal pancreatectomy
Roboticapplication for pancreatectomy
Current update/controversial issue
Role of extended resection for PDAC
Concept of customized surgery
5. Morbidity and perioperative care
Pancreatic fistula
Delayed emptying
Postoperative bleeding
Other rare complication
Late metabolic complication
Current update/controversial issue
ERAS
Drain care after pancreatoduodenectomy
6. Nonoperative therapy for pancreatic cancer
Adjuvant therapy
Palliative chemotherapy. - Radiation therapy.