Pathology and Pathobiology of Rheumatic Diseases glows with the uncommon precision of the pathologist, the clarity of the tea cher, and the unswerving commitment of the investigator. Fass bender has produced a major contribution to the literature of rheumatic diseases. The practical experience and wisdom brought together in this book, substantiated by excellent exam ples of histopathology, produce a landmark for all who have made the study of rheumatic diseases their profession. The enor mous achievements made in molecular biology, genetics, struc tural biochemistry, and clinical science have been assembled in this book to interact in a meaningful way with the anatomical histology of the rheumatic diseases. It is not easy for any single investigator to paint the picture of a disease process, from its clinical description to its mechanisms, and then to a defined hypothesis, and finally an understanding. Nonetheless, Fassbender has done this in a clear and convincing way that integrates our current knowledge of this group of dis eases. Scientific discovery in medicine moves from the bedside to the bench, back to the bedside, and then back to the bench, etc. It is this iterative process of new observation and new discovery that has given us the achievements in medicine over the past century.

1 Inflammation and Its Morphological Manifestation

2 Rheumatic Fever
3 Rheumatoid Arthritis
4 Sjögren's Syndrome
5 Juvenile Chronic Arthritis
6 Seronegative Spondarthritides
7 Behçet's Syndrome
8 Lyme Disease
9 Systemic Lupus Erythematosus
10 Systemic Sclerosis
11 Eosinophilic Fasciitis and Related Syndromes
12 Polymyalgia Rheumatica and Giant Cell Arteritis
13 Vasculitides
14 Idiopathic Inflammatory Myopathies
15 Fibromyalgia Syndrome
16 Osteoarthritis
17 Crystal-Associated Arthropathies
18 Ochronosis
19 Bacterial Arthritis
20 Bacterial Superinfection
21 AIDS and Rheumatism
22 Tuberculosis
23 Sarcoidosis
24 Viral-Induced Arthritides
25 Villo-Nodular Synovitis
26 Baker's Cyst
27 Carpal Tunnel Syndrome
28 Dupuytren's Contracture
29 De Quervain's Tenosynovitis and Trigger Finger (Tendopathia Nodosa)
30 Bursae
31 Ganglion
32 Possibilities and Limitations of Synovial Biopsy
References.