This book is a collection of case-based questions, directed towards and meticulously selected to cover the most common and important aspects of pediatric autoimmune disorders. Autoimmune disorders of infancy and childhood, rheumatological disorders, dermatologic autoimmune disorders, autoinflammatory disorders, and clinical immunology in solid organ and hematopoietic stem cell transplantation are among the topics covered.

 Each chapter starts with a case description followed by a series of 5-6 multiple choice questions (MCQ), presenting the flow from diagnosis to treatment in a step-wise, logical manner. The text guides the reader through the stream of real clinical practice from initial presentation, differential diagnosis, next best step, lab data, and definitive diagnosis to management and adverse effects of therapy. This MCQ format along with precise, yet detailed answer ensure a quick, reality learning to the reader.

 The book provides a quick guide and hands-on learning experience for pediatricians, hematologists, immunologists, transplant specialists, pulmonologists, as well as PhD and post-graduate researchers around the world.

Farzaneh Rahmani is a MD, MPH graduate from Tehran University of Medical Sciences. A three times winner of the Avicenna Student Award as outstanding young scientist in 2015, 2017, and 2019, and the National Outstanding Student of the Ministry of Health in 2019, she has achieved academic excellence way ahead of her peers. More than 40 publications and 2 book titles published within only 4 years of research activity report of a scientific future that promises to be bright for her.

Nima Rezaei is a MD, PhD in clinical immunology and human genetics. Having finished his PhD, he was awarded a fellowship in Clinical Immunology and Bone Marrow Transplantation, Pediatric Immunology and Infectious Diseases in Northern Supra Regional Bone Marrow Transplant Unit for SCID and Related Disorders in the Newcastle General Hospital.

He has since authored more than 700 publications, including the Springer, 'Primary Immunodeficiency Diseases', Immunology of Aging' and 'Cancer Immunology' series, for which he was awarded the 10^th, 16^th and 17^th Avicenna Award for the book of the year. He was recognized as the distinguished young researcher to the prestigious Rhazi Award in in Medical Science Research on 2006 and 2012. In 2017 he was recognized by the National Academy of Medical Sciences, as 'Iran's Best Medical Researcher of the Past Decade''. The Iranian Primary Immunodeficiency Diseases Registry (IPIDR) is indeed one of his great scientific legacies, enrolling thousands of patients since 1999.