This book comprises a collection of categorized case-based questions, directed and meticulously selected to cover the most common and most important aspects of immunodeficiency diseases. Immunodeficiency disorders of infancy and childhood such as antibody deficiencies, phagocyte defects and defects in innate immunity are addressed among others. Each chapters starts with a brief of the initial presentation and lab data of the patient, followed by a series of 5-6 multiple choice questions (MCQs), leading the reader to the diagnosis and best of practice in a step-wise manner. This MCQ format along with precise, yet detailed answer ensures a quick, case-based, reality learning to the reader. This comprehensive MCQ series, is an essential reading material that a pediatric clinician, hematologist, immunologist, transplant specialist, or pulmonologist, can not afford to miss.

1.Introduction to Primary Immunodeficiencies

2. Workup of Recurrent Respiratory Infections and a Positive Family History
3. Pseudomonas Meningitis
4. Fever and Sleepiness
5. Recurrent Pneumonia
6. Developmental Regression
7. Recurrent Ear Infections and Pneumonia
8. Positive Urine Culture for Klebsiella pneumoniae
9. Brothers with Recurrent Sinopulmonary Infections and Chronic Lung Disease
10. Recurrent Infections and Arthritis
11. Initial Diagnosis of Neutropenia and Later Crohn's Disease
12. Diagnosis of "Sweat-Chloride Negative" Cystic Fibrosis
13. Diagnosis of Sarcoidosis
14. Refractory Crohn's disease
15. Asthma Which Was Not Asthma
16. Generalized Lymphadenopathy and Hypogammaglobulinemia after Abdominal Trauma
17. Weakness and Anemia
18. Normal Primary Care Workup for Recurrent Sinopulmonary Infections
19. Recurrent Sinusitis and Persistent Giardia Infection
20. Recurrent Respiratory Infections
21. SiblingsPresenting with Mild and Severe Lymphoproliferation
22. Non-Malignant Lymphoproliferation
23. Portal Hypertension and Progressive Lymphoproliferation
24. Recurrent Otitis and Upper Airway Obstruction
25. Recurrent Pneumonia
26. A Growing BCG Lesion
27. Respiratory Distress and hypoxemia
28. A Boy with Burdened Family History, Candidiasis and Diarrhea
29. Failure to Thrive
30. Recurrent Respiratory Infection and Hypereosinophilia
31. Neonatal Jaundice and Leukopenia, Microcephaly, Recurrent Infections and Failure to Thrive
33. Widespread Erythema and Skin Desquamation
34. Failure to Thrive, Rash and Fever
35. Autoimmune Cytopenia
36. Recurrent Respiratory Tract Infections
37. Protracted Diarrhea and Hypogammaglobulinemia
38. Gingivitis and Recurrent Tonsillitis
39. Respiratory Distress
40. Intestinal Cryptosporidiosis
41. Shortness of Breath
42. Pneumocystis jiroveciPneumonia without Failure to Thrive
43. Recurrent Infections and CNS Vasculitis
44. Recurrent Infections and Widespread Warts
45. Rash and Several Food Allergies
46. Sever Atopic Disease and Infections
47. Acute Mastoiditis
48. Chronic Papulovegetative Ulcer on Penis
49. Fever after DPT Vaccination
50. Recurrent Bronchiolitis
51. Oral Ulcers and Candidiasis
52. Neutropenia and Myelodysplasia
53. Loss of Appetite and Neutropenia
54. Delayed Umbilical Cord Separation
55. Recurrent Pneumonitis
56. Recurrent Sepsis, Leukocytosis and Bleeding Tendency
57. Maculopapular Rash on BCG Site
58. Recurrent Perianal Abscesses
59. Infected Hemangiomas
60. Recurrent Invasive Bacterial Infections
61. Cervical Lymphadenitis
62. Failure to Thrive and Nasal Obstruction
63. Inflammatory Bowel Disease and Frequent Skin Abscesses
64. Necrotizing Liver Granuloma
65. Constrictive Aspergillosis Pericarditis
66. Lung Abscess
67. Lethargy in a Toddler
68. Recurrent Cold Suppurative Granulomatous Lymphadenitis
69. Repetitive Fistulizing Lymphadenopathy and Hematochezia
Chapter 70. Twins with Recurrent Candida Infections
Chapter 71. Recurrent Stomatitis and Upper Respiratory Tract Infections
Chapter 72. Oral Thrush and Onychomycosis
Chapter 73. Oral Moniliasis and Failure to Thrive
Chapter 74. Refractory Oral Thrush
Chapter 75. Kidney Malformation and Persistent Neutropenia
Chapter 76. Severe Pancytopenia
Chapter 77. Silvery Hair
Chapter 78. Fever and Blonde Skin
Chapter 79. Probable Sepsis
Chapter 80. Skin Abscess and Blonde Hair
Chapter 81. Recurrent Infections and Easy Bruising
Chapter 82. Fever and Skin Eruption
Chapter 83. Cervical Lymphadenopathy and Nasopharyngeal Mass
Chapter 84. Lymphadenopathy and Splenomegaly
Chapter 85. Anemia and Neutropenia
Chapter 86. Hemolytic Anemia and Lymphadenopathy
Chapter 87. Recurrent Infections and Chronic Diarrhea
Chapter 88. Recurrent Infections, Cytopenias and Lung Disease
Chapter 89. Short Stature, Prolonged Feverand Lymphoproliferation
Chapter 90. Siblings with Nail Dystrophy and Photophobia
Chapter 91. Chronic Diarrhea and Failure to Thrive
Chapter 92. Rash and Diarrhea
Chapter 93. Recurrent Infections, Enteropathy and Granulomatous Lung Disease
Chapter 94. Chronic Diarrhea
Chapter 95. Early-Onset Inflammatory Bowel Disease
Chapter 96. Recurrent Febrile Episodes and Abdominal Pain
Chapter 97. Episodic Fever and Lymphadenopathy
Chapter 98. Periodic Fever Syndrome and Developmental Delay
Chapter 99. Periodic Fever and Maculopapular Rash
Chapter 100. Long Episodes of Rash and Fever
Chapter 101. Long-Lasting History of Urticaria
Chapter 102. Rash and Fever since Two Weeks of Age
Chapter 103. Aseptic Meningitis
Chapter 104. Recurrent Fever and Sore Throat
Chapter 105. Recurrent Fever and Stomatitis
Chapter 106. Prolonged Fever and Swollen Joints
Chapter 107. Skeletal Pain in Knee and Clavicle
Chapter 108. Bone Pain in Upper Leg, Hip, Lower Back
Chapter 109.Enterocolitis Followed by Recurrent Sepsis-Like Episodes
Chapter 110. Recurrent Febrile Attacks, Myalgia and Livedo Reticularis
Chapter 111. Sudden Dizziness, Somnolence and Diplopia
Chapter 112. Recurrent Chest Pain
Chapter 113. Irregular Recurrent Fever
Chapter 114. Fever, Headache and Photophobia
Chapter 115. Recurrent Meningitis
Chapter 116. Lupus, Macrophage Activation Syndrome and Invasive Infections
Chapter 117. Recurrent Edema
Chapter 118. Recurrent, Non-Pitting Edema of Lips, Extremities and Genitalia
Chapter 119. Recurrent Abdominal Pain
Chapter 120. Laryngeal Edema
Chapter 121. Lips Angioedema
Chapter 122. Chronic Diarrhea
 Recurrent Edema and Respiratory Infections
Chapter 123. Otitis Media and Gait Disturbance
Chapter 124. Regression of Her Ability to Walk
Chapter 125. Microcephaly and a History of Recurrent Respiratory Infections
Chapter 126. Recurrent Respiratory Infections and Chronic Hepatic Disease
Chapter 127. Family Memberswith Congenital Heart Disease and Hypogammaglobulinemia
Chapter 128. Erythrodermic Rash and Seizures
Chapter 129. Bloody Diarrhea
Chapter 130. Leukocytoclastic Vasculitis
Chapter 131. Progressive Renal Failure with Lymphopenia
Chapter 132. Bloody Stool and Recurrent Infections
Chapter 133. Idiopathic Thrombocytopenic Purpura
Chapter 134. Allergy and Recalcitrant Wart
Chapter 135. Recurrent Cutaneous and Sinopulmonary Infections
Chapter 136. Cold Abscesses and Lymphadenopathy
Chapter 137. Recurrent Pneumonia and Fracture in the Femur
Chapter 138. Fractures Following Minimal Trauma
Chapter 139. Cough and Dyspnea
Chapter 140. Skin Abscesses
 Eczema and Lymphopenia
Chapter 141. Lymphopenia and Neutropenia
Chapter 142. Red Peeling
Chapter 143. BCGosis and Hyperferritinemia
Chapter 144. Mycobacterial Infection, Ectodermal Dysplasia and Thrombocytopenic Purpura
Chapter 145. Progressive Hypotonia with Lymphopenia
Chapter 146. Painless Hematuria and Repaired Patent Ductus Arteriosus
Chapter 147. Intractable Diarrhea and Failure to Thrive
Chapter 148. Alopecia, Hypothyroidism, Leukopenia and Hypogammaglobulinemia.