This volume provides readers with the most updated scientific information on the efficacy and safety of medicines for children and adolescents. The book enriches the understanding of pediatric pharmacotherapy for health professionals, regulatory agencies, pharmaceutical companies and learned societies. It contains important information on the pharmacodynamics and pharmacokinetics of drugs. It summarizes the latest investigations on the effects of pharmacological treatments in relation to and dependent on age, gender, fat mass and disease status. Therefore and importantly, this volume reviews the latest data on how pharmacotherapy has to be adjusted and personalized in regards to stages of development and during the pediatric lifespan from neonate through adolescence.  In addition, the topic of rare diseases and special challenges for pharmacotherapy will be included and will provide readers with the necessary knowledge to handle complex diseases and treatment strategies especially in relation to pharmacotherapy of rare and orphan diseases.

<p>Anti-epileptic drugs in pediatrics

Current and new therapies for Duchenne Muscular Dystrophy
Lysosomal diseases
Mitochondriopathies
Endocrinology thyroid, pituitary, growth stimulant, growth reduction
Bone disease - bisphosphonates
Diabetes type 1 and 3 (insulin; sulfonylurea; others)
Diabetes type 2 (metformin etc.)
Dermatology - part 1 urticaria, atopic dermatitis
Dermatology part 2, ichtyosis, psoriasis
Cardiovascular  part 1- catcholamines, inotropic
Cardiovascular part 2 - antiarhythmica, anti hypertensives
Nephrology - dialysis
How to use drugs in obese children and adolescents<b>
</b>Haematology - CSFs, erythropoietin
Antiretroviral/HIV
Clinical pharmacology and pharmacometrics to better understand physiological changes during pregnancy and neonatal life<b>
</b>Antihelminth treatment
Inflammatory bowel disease
Constipation; laxatives
Psychiatric diseases in children and adolescents
Oncology - cell reducing agents part 1, part 2,part 3
Immunosuppressants - organ transplantation
Bone marrow/stem cell transplantation
Narcotic sparing approaches and the shift towards paracetamol in neonatal intensive care
Disorders of puberty: pharmacotherapeutic strategies for management.</p>