Percutaneous Collagen Induction with Microneedling is a minimally invasive technique widely used to treat numerous dermatologic conditions such as facial and body scars, melasma, wrinkles, skin laxity, stretch marks, alopecies, vitiligo and scleroderma. Microneedling can also be used to optimize transdermal drug delivery for many substances. 

This technique uses modern microneedling devices containing multiple fine needles, typically 0.5 to 2.5 mm in length, which are mounted on a barrel and rolled onto the skin to create numerous perforations into the stratum corneum and the papillary dermis. These micro-wounds initiate the release of growth factors, triggering collagen and elastin formation, which results in dermal remodeling and skin resurfacing. 

This book provides a step-by-step approach to microneedling, based on the authors' more than ten years of experience with the technique, during which they have treated more than 3,000 patients in Brazil for numerous dermatologic conditions. Richly illustrated throughout, it includes over 400 illustrations.

1. Fundamentals of Percutaneous Collagen Induction (PCI) with needles. - 2. Classification and characteristics of the injury provoked by PCI. - 3. Devices for PCI. - 4. Pain management in PCI - Analgesia and Anesthesia. - 5. Preparing the skin for PCI and Postoperative management. - 6. Histopathological evidences of the Percutaneous Collagen Induction with Microneedling. - 7. Managing complications in PCI. - 8. PCI in aging skin. - 9. PCI in the treatment of melasma. - 10. PCI Correcting post-inflammatory hyperpigmentation. - 11. Correcting acne scars using PCI. - 12. Correcting  after accident scars using PCI. - 13. Correcting post-surgical scars using PCI. 14. Correcting post burn scars using PCI. - 15. Correcting High and Hypertrophic Scars with PCI. - 16. Correcting stretch marks using PCI. - 17. Correcting laxity and cellulitis using PCI. - 18. PCI and transcutaneous drug delivery. - 19. PCI associate to fillings and botulin toxin. - 20. PCI in the treatment of the alopecies. - 21. PCI in the treatment of scleroderma. - 22. PCI in the hypochromias and achromias. - 23. PCI associated to Intense Pulsed Light. - 24. PCI associated to peelings. - 25. Fundamentals of the Dermal Tunneling (DT), a subincision(TM) variant. - 26. Dermal Tunneling in the treatment of depressed scars. - 27. Dermal Tunneling in the treatment of  Static Wrinkles and Grooves. - 28. PCI  associated to Multi-Needles Radiofrequency for the treatment of periorbital and perioral wrinkles and laxity. - 29. PCI associated to Multi-Needle radiofrequency for treatment of scars. - 30. PCI on Ethnic Skin.