This truly comprehensive reference, in a mini-series format with five volumes, offers a detailed description of both well-known and recently introduced methods for percutaneous penetration enhancement. The first three volumes are devoted to the broad range of chemical methods used to enhance the skin delivery of drugs, including the vast variety of chemical penetration enhancers, drug and vehicle manipulation strategies, nanocarriers, and many others. The fourth volume discusses the diverse physical methods used in penetration enhancement, such as sonophoresis, iontophoresis, electroporation, microporation, laser ablation, and microneedles. Determination of drug penetration is covered in the final volume, with a focus especially on mathematics in skin permeation and modern analytical techniques adapted to assess and measure penetration. This edition of Percutaneous Penetration Enhancers will be an invaluable resource for researchers, pharmaceutical scientists, practitioners, andalso students.

THE SKIN

The Skin Structure And Penetration Pathways Through The Skin
The Increasing Importance Of The Follicular Route In Dermal And Transdermal Drug Delivery
The Importance Of SC Lipid Organization For Skin Barrier Function
Nanostructure Of The Epidermal Extracellular Space Investigated By Cryo-Electron Microscopy And Tomography
The Correlation Between Transepidermal Water Loss And Percutaneous Drug Absorption
Influence Of Excipients On The Stratum Corneum Lipids And Epidermal Tight Junctions
PENETRATION ENHANCEMENT TECHNIQUES IN SKIN DELIVERY
Classification Of Penetration Enhancement Techniques
DRUG MANIPULATION STRATEGIES IN PENETRATION ENHANCEMENT
Selection Of A Proper Prodrug For Penetration Enhancement
Supersaturated Solutions For Penetration Enhancement
Eutectic Systems For Penetration Enhancement
INFLUENCE OF VEHICLE EFFECTS IN PENETRATION ENHANCEMENT
Dermal and Transdermal Formulations
EMULSIONS (AS SKIN DELIVERY SYSTEMS) AS VEHICLES FOR SKIN DELIVERY
GELS AS VEHICLES FOR SKIN DELIVERY.