This book provides surgeons and oncologists with a well-founded and detailed overview of the available treatment options for peritoneal malignancy and differential selection of the appropriate forms of therapy. Systemic chemotherapy options are also considered, as are surgical cytoreduction (CRS) and all forms of intraperitoneal chemotherapy (IPC) especially hyperthermic IPC (HIPEC), and immunotherapy, including specific procedures such as PIPAC.

Subsequent chapters address perioperative care, complications and recurrences, as well as psycho-oncological, palliative medical and nursing care. The process of parietal and visceral peritonectomy in the large and small intestine is additionally illustrated by three video clips accessible online. Covering a broad range of aspects, including peritoneal metastasis and intraperitoneal chemotherapy, the book offers a valuable tool for surgeons, oncologists and anesthesiologists alike.

I Basics

1 Anatomy and pathology of the peritoneum
2 Pharmacovigilance of topical chemotherapy in the peritoneum
II Diagnostics and natural course
3 Imaging diagnostics of tumors of the peritoneum
4 Role of laparoscopy in the diagnosis of tumors of the peritoneum
5 Scoring systems for CRS and HIPEC
6 Natural course of peritoneal carcinomatosis
III Therapy options of systemic therapy
7 Inductive preoperative chemotherapy for peritoneal metastases of tumors of the upper GI tract
8 Inductive preoperative chemotherapy for peritoneal metastases of tumors of the lower GI tract including appendiceal carcinoma
IV Treatment options for surgical cytoreduction
9 Procedures of parietal and visceral peritonectomy in the upper abdomen
10 Technique of visceral and parietal peritonectomy in the lower abdomen
11 Procedures of parietal and visceral peritonectomy interenterically
12 Cytoreduction - preparation devices
V therapy options of intraperitoneal therapy and experimental approaches
13 Application of IPC, HIPEC and PIPAC
14 Cytokine-induced senescence: an experimental therapy for peritoneal tumors
15 Mechanism of action and experimental and clinical data on regional hyperthermia
16 HIPEC in childhood
VI Potentially curative approach
17 Importance of intraperitoneal chemotherapy as a prophylaxis after curative resection of a gastrointestinal carcinoma
18 Indication of CRS and HIPEC in Pseudomyxoma peritonei
19 Significance of CRS and HIPEC in mesothelioma
20 Indication of CRS and HIPEC in peritoneal metastatic gastric carcinoma
21 Indication of CRS and HIPEC in peritoneal metastases of colorectal carcinomas
22 Indication of CRS and HIPEC in peritoneal metastases of ovarian cancer
23 Indication of CRS and HIPEC in peritoneal metastases of NET and small intestinal carcinomas
24 Indication of CRS and HIPEC in peritoneal metastases of pancreatic carcinomas
25 Indications of CRS and HIPEC in Incidentally Detected Peritoneal Carcinomatosis
 VII VII Palliative  treatment attempt of advanced peritoneal metastasis
26 Importance of systemic chemotherapy in advanced peritoneal metastasis
27 Importance of PIPAC in advanced peritoneal metastasis
VIII Complications in the Palliative Chemotherapy of Peritoneal Cancer
28 Complications in the Palliative Chemotherapy of Peritoneal Cancer
29 Cytoreductive surgery for complications of peritoneal carcinomatosis
30 IPEC, HIPEC, Bidirectional Chemotherapy and Immunotherapy in Aggressive Peritoneal Metastasis
IX Perioperative treatment and prophylaxis of treatment related complications
31 Preoperative Management: Risk Assessment, Conditioning, Nutritional Aspects, Special Preparation, Including Bowel
32 Safety Considerations for Intraoperative Use of Cytostatic Agents
33 Preventing Complications of Cytoreductive surgery and Hyperthermic Intraperitoneal Chemotherapy
34 Nutritional Concepts in Patients with Peritoneal Tumors
35 Perioperative management
X Quality of life
36 Quality of life at CRS and HIPEC
37 PIPAC Therapy and Quality of Life
XI Recurrent diesease
38 Follow-Up to Prevent Recurrence of Peritoneal Malignancies
39 Localization of Localization of Peritoneal Tumor Recurrence
40 Treatment Options for Peritoneal Tumor Recurrence
XII  Environmental Aspects
41 Importance of Psycho-Oncology for Tumors of the Peritoneum
42 Nursing Aspects of Peritoneal Surface Malignancy
XIII Guidelines and centres
43 Guideline preparation and center development for the treatment of peritoneal tumors in Germany
44 Guideline preparation and center development for the treatment of peritoneal tumors in Switzerland
Service part
45 Checklists for the treatment of tumors of the peritoneum. Framework SOP
Index.