Practical Oncologic Molecular Pathology

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Practical Oncologic Molecular Pathology

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This book is a review and high-yield reference on the clinical molecular diagnostics of malignant neoplasms. It aims to address the practical questions frequently encountered in the molecular oncology practice, as well as key points and pitfalls in the clinical interpretation of molecular tests in guiding precision cancer management. The text uses a Q&A format and case presentations, with emphasis on understanding the molecular test methods, diagnosis, classification, risk assessment and clinical correlation. Starting with an update on the molecular biology of cancer, the book focuses on the topics related to molecular diagnostics and genetics-based precision oncology. Separate chapters are dedicated to discussion of the bioinformatics for the analysis of genetic/genomic data generated from molecular assays, and quality control (QC)/quality assurance (QA) programs in the clinical laboratories; both are critical in producing high quality results for clinical care of cancer patients. These are followed by organ system-based reviews and discussions on the molecular genetic abnormalities and related tests covering diverse types of common to rare malignant neoplasms. This book also provides up-to-date knowledge related to malignant neoplasms, discusses the established as well as evolving requirements for pathologic diagnosis of these malignancies. It also discusses the cost effective utilization of molecular tests in clinical oncology.
Written by experts in the field, Practical Oncologic Molecular Pathology serves as a valuable reference for practicing pathologists, fellows, residents and other health care professionals. 

The Molecular Pathobiology of Malignant Process and Molecular Diagnostic Testing for Cancer
Molecular Diagnostic Methods
Bioinformatics Analysis In Molecular Pathology
Quality Assurance and Quality Control in Molecular Diagnostic Laboratories
Breast And Gynecologic Tumors
Tumors of Central Nervous System
Lung Cancer
Gastrointestinal, Hepatobiliary, and Pancreatic Tumors
Skin Tumors
Soft Tissue Tumors
Genitourinary Tumors
Hereditary Cancer Syndromes and Inherited Cancer Risks
Acute Myeloid Leukemia
Myeloproliferative Neoplasms, Myelodysplastic /myeloproliferative Neoplasms and Myelodysplastic Syndromes
Precursor Lymphoid Neoplasms
Mature B-Cell Neoplasms
Plasma Cell Neoplasms
Mature T- and NK-cell Neoplasms
Histiocytic and Dendritic Cell Neoplasms
Bone Marrow Engraftment Analysis.
ISBN 978-3-030-73226-4
Artikelnummer 9783030732264
Medientyp Buch
Auflage 1st ed. 2021
Copyrightjahr 2021
Verlag Springer, Berlin
Umfang XII, 449 Seiten
Abbildungen XII, 449 p. 192 illus., 181 illus. in color.
Sprache Englisch