The number of diagnosed cases of primary immunodeficiency diseases (PIDs) - a group of inborn disorders of the immune system - is growing rapidly, but misdiagnosis or late diagnosis still occurs in a significant number of patients, with serious consequences. This is the second edition of a practical reference textbook on PIDs that has been widely welcomed by scientists and clinicians from around the world. The new edition has been extensively revised to reflect advances in knowledge and includes various PIDs not previously covered. For each disease, information is provided on definition, etiology, clinical manifestations, diagnosis, and management. This book will represent an ideal resource for specialists when engaging in diagnosis, clinical decision-making, and treatment planning. It will also prove invaluable for doctors in training and other physicians and nurses who wish to learn more about PIDs.

Nima Rezaei gained his medical degree from Tehran University of Medical Sciences in 2002 and subsequently obtained an MSc in Molecular and Genetic Medicine and a PhD in Clinical Immunology and Human Genetics from the University of Sheffield, UK. He also spent a short-term fellowship of Pediatric Clinical Immunology and Bone Marrow Transplantation in the Newcastle General Hospital. Since 2010, Dr. Rezaei has worked at the Department of Immunology and Biology, School of Medicine, Tehran University of Medical Sciences; he is now the Vice Dean of International Affairs, School of Medicine, Tehran University of Medical Sciences, the Director of Global Academic Program, Tehran University of Medical Sciences, and the co-founder and Deputy President of the Research Center for Immunodeficiencies. In addition, Dr. Rezaei is an Honorary Associate Staff at the Department of Infection and Immunity, School of Medicine and Biomedical Sciences, University of Sheffield. He is also the founder and president of Universal Scientific Education and Research Network (USERN). Dr. Rezaei has already been the Director of more than 50 research projects and has designed and participated in several international collaborative projects. Dr. Rezaei is an editorial assistant or board member for more than 20 international journals. He has edited more than 10 books, has presented more than 350 lectures/posters in congresses/meetings, and has published more than 500 articles in the international scientific journals during last decade.