Optic nerve sheath meningioma (ONSM) is a rare tumour. Cases are usually separated into primary ONSM, which arises either intraorbitally or, less commonly, intracanalicularly, and secondary ONSM, which arises intracranially and subsequently invades the optic canal and orbit. This is the first book to cover all important aspects of the diagnosis and treatment of primary ONSM. After a general introduction, individual chapters discuss the clinical presentation, clinical examination and diagnosis, imaging, and histology. Treatment options are then addressed in detail, with special emphasis on external beam radiation therapy, and in particular stereotactic fractionated radiation therapy. The latter has recently produced consistently good results and is now considered the emerging treatment of choice for the vast majority of patients with primary ONSM. This well-illustrated book will prove invaluable to all practitioners who encounter primary ONSM in their clinical work.
1;DEDICATION;5 2;Foreword;7 3;Preface;9 4;Contents;11 5;Overall Introduction, Problem Definition, Incidence;13 5.1;Introduction;13 5.2;Incidence;16 6;Clinical Presentation;19 6.1;Introduction;19 6.2;Typical Presentation;20 6.3;Atypical Clinical Presentation;25 7;Clinical Evaluation of Primary Optic Nerve Sheath Meningioma;29 7.1;Introduction;30 7.2;Meningioma of the Optic Nerve and Orbit;30 7.3;Epidemiology;31 7.4;Special Cases;40 7.5;Differential Diagnosis;42 7.6;A Suggested Approach to Clinical Evaluation;45 8;Imaging Diagnosis of the Optic Nerve Sheath Meningioma;51 8.1;Introduction;51 8.2;Clinical Presentation;52 8.3;Imaging Features;52 8.4;Special Situations;58 8.5;Differential Diagnosis of Optic Nerve Enlargement;58 8.6;Miscellaneous;63 9;Histology and Molecular Genetics;67 9.1;Incidence and Epidemiology;67 9.2;Histological Classification;68 9.3;Meningioma Genetics;72 10;Surgery in Primary Optic Nerve Sheath Meningioma;79 10.1;Introduction;80 10.2;treatment Goals;80 10.3;A Subset of Data on Surgery in Primary ONSM;80 10.4;General Indications for Surgical Intervention;82 10.5;Canalicular Involvement;87 10.6;Conclusion;87 11;Conventional Radiation therapy in Primary Optic Nerve Sheath Meningioma;89 11.1;Postoperative Radiation Therapy;89 11.2;Exclusive Conventional Radiation therapy;92 12;3D Conformal RT;97 12.1;Introduction;97 12.2;Principles and techniques of 3D Conformal Rt;98 12.3;Literature on 3D Conformal Rt for ONSM;102 12.4;Treatment Related Toxicity;105 13;Intensity Modulated Radiotherapy for Optic Nerve Sheath Meningioma;107 13.1;Introduction;107 13.2;Radiobiological Considerations: Radiation Dose and Fractionation;108 13.3;Complications;109 13.4;Contraindications to Radiotherapy;110 13.5;Intensity Modulated Radiotherapy;110 14;Stereotactic Radiation therapy in Primary Optic Nerve Sheath Meningioma;117 14.1;Introduction;117 14.2;Stereotactic Radiosurgery;118 14.3;Stereotactic Fractionated Radiation therapy;119 15;Subject Index;141 16;List of Contributors;145
Jeremic, Branislav
Pitz, Susanne
| ISBN | 9783540775584 |
|---|---|
| Artikelnummer | 9783540775584 |
| Medientyp | E-Book - PDF |
| Auflage | 2. Aufl. |
| Copyrightjahr | 2008 |
| Verlag | Springer-Verlag |
| Umfang | 139 Seiten |
| Sprache | Englisch |
| Kopierschutz | Digitales Wasserzeichen |
