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This book provides a comprehensive overview of the management of brain and skull base tumors. It features detailed insight into the intrinsic molecular biology, anatomical foundation, radiological planning, surgical execution, and the novel therapeutics that guide today's treatment regimens. The first section features concepts related to the epidemiology and pathological basis of disease processes, including relevant cellular and molecular biology. In the second section, integral anatomical foundations and principles are covered including microsurgical anatomy of the cerebrum, white matter tracts, ventricles, brainstem, skull base, advancements in radiological imaging, and cognitive examinations. Surgical approaches and how to execute these procedures are then subsequently discussed in the third part of the work. 


Principles of Neuro-Oncology: Brain & Skull Base is a practically applicable guide to the latest treatment techniques available to treat these patients. Therefore, it is an indispensable resource for all physicians who utilize these methodologies in their day-to-day practice.




1. Introduction.- Part 1: Tumor Biology

2. Epidemiology
3. Molecular Biomarkers in Tumors
4. Molecular Biomarkers in Brain Metastasis
5. Pathology Classification.- Part 2: Planning
6. Microsurgical Anatomy of the Cranial Base and the White Matter Tracts (3D)
7. Microsurgical Anatomy of the Brainstem
8. Advances in Neuroimaging
9. DTI: planning for skull base and intra-axial tumors approaches
10. Neurological Examination
11. Neuro-Psychiatric Examination
12. Embolization of the Cranial Base Tumors.- Part 3:RT
13. Whole Brain Radiation
14. Radiosurgery (LINAC).- Part 4: Chemotherapy
15. Chemotherapy
16. Intratumoral Chemotehrapy
17. Genetic Therapy ( Gliomas)
Part 5: Surgery
18. Surgical Radial Corridors Dorsal and Ventral Approaches to the Cranial Base)
19. Parafascicular Surgery (Chassis)
20. Craniofacial Approaches
21. Early experience with the ROVOT-m in Neurosurgery
22. Awake Surgery in Brain Tumors
23. Transclival Approaches
24. Surgery in Spine Tumor
25. Infratemporal Fossa and Pharapharyngeal Space Surgery
26. 360 around of the Craniocervical Junction
27. Neuroendoscopy
28. 360 around of the Orbit.- Part 6: Tumors
29. Surgery in Gliomas
30. Surgery in Meningiomas of the Anterior Cranial Base (EEA)
31. Surgery in Meningiomas of the Anterior Cranial Base (Open)
32. Surgery in Meningiomas of the Middle Cranial Base
33. Surgery in Meningiomas of the Posterior Cranial Base
34. Surgery in CPA angle
35. Surgery for Craniopharyngioma
36. Pituitary Surgery (EEA and Open)
37. Yugular Schawannomas Surgery
38. Surgery of the Intraventricular Tumors
39. Brain Metastasis Surgery
40. Surgery of Esthesioneuroblastoma
41. Chordomas Surgery
42. Brainstem Surgery.


ISBN 978-3-030-54878-0
Artikelnummer 9783030548780
Medientyp Buch
Auflage 1st ed. 2021
Copyrightjahr 2020
Verlag Springer, Berlin
Umfang XIII, 982 Seiten
Abbildungen XIII, 982 p. 500 illus., 425 illus. in color. With online files/update.
Sprache Englisch