Process integration has been one of the most active research fields in Biochemical Engineering over the last decade and it will continue to be so if bioprocessing is to become more rational, efficient and productive. This volume outlines what has been achieved in recent years. Written by experts who have made important contributions to the European Science, Foundation Program on Process Integration in Biochemical Engineering, the volume focuses on the progress made and the major opportunities, and in addition on the limitations and the challenges in bioprocess integration that lie ahead. The concept of bioprocess integration is treated at various levels, including integration at the molecular, biological, bioreactor and plant levels, but also accounting for the integration of separation and mass transfer operations and biology, fluid dynamics and physiology, as well as basic science and process technology. TOC:Editorial: S.-O. Enfors, L. van der Wielen, U. von Stockar: Process Integration Challenges in Biotechnology Yesterday, Today and Tomorrow.- U. von Stockar, L. van der Wielen: Back to Basics: Thermodynamics in Biochemical Engineering.- S. Schmalzriedt, M. Jenne, K. Mauch, M. Reuss: Integration of Physiology and Fluiddynamics.- A. Bruggink, L. van der Wielen: A Fine Chemical Industry for Life Science Products: Green Solution to Chemical Challenges.- P. Fernandes, D.M.F. Prazeres, J.M.S. Cabral: Membrane-Assisted Extractive Bioconversion.- D. Stark, U. von Stockar: In-situ Product Removal in Whole Cell Biotechnolgy During the Last 20 Years.

Back to Basics: Thermodynamics in Biochemical Engineering

Integration of Physiology and Fluid Dynamics
A 'Fine' Chemical Industry for Life Science Products: Green Solutions to Chemical Challenges
Membrane-Assisted Extractive Bioconversions
In Situ Product Removal (ISPR) in Whole Cell Biotechnology During the Last Twenty Years.