Progress in the Chemistry of Organic Natural Products 115
Progress in the Chemistry of Organic Natural Products 115
This book describes current understandings and recent progress into a varied group of natural products. In the first chapter the role that total synthesis may play in revising the structures proposed for decanolides, which are ten-membered lactones found primarily in fungi, frogs, and termites is presented. The following chapter presents the development of the intriguing plant-derived sesquiterpene lactone, thapsigargin, a potent inhibitor of the enzyme, SERCA (sarco-endoplasmic Ca2+ ATPase), which has potential as a lead compound to treat cancer. The third chapter covers the potential of various plant phenolic compounds for treating the tropical and sub-tropical infectious disease, leishmaniasis. In addition the volume presents recent advances related to the plant alkaloid, cryptolepine, which is of particular interest as a lead for the treatment of malaria, trypanosomiasis, and cancer.
Antileishmanial Activity of Lignans and Neolignans
Cryptolepine as a Lead to new Antiprotozoal Agents
Biologically Active Constituents from Plants of the Genus Xanthium.
Total Synthesis of Decanolides (Nonanolides) with a Special Focus on Olefin Metathesis
From Plant to Patient: ThapsigarginAntileishmanial Activity of Lignans and Neolignans
Cryptolepine as a Lead to new Antiprotozoal Agents
Biologically Active Constituents from Plants of the Genus Xanthium.
Kinghorn, A. Douglas
Falk, Heinz
Gibbons, Simon
Asakawa, Yoshinori
Liu, Ji-Kai
Dirsch, Verena M
| ISBN | 978-3-030-64852-7 |
|---|---|
| Artikelnummer | 9783030648527 |
| Medientyp | Buch |
| Auflage | 1st ed. 2021 |
| Copyrightjahr | 2021 |
| Verlag | Springer, Berlin |
| Umfang | VII, 203 Seiten |
| Abbildungen | VII, 203 p. 144 illus., 42 illus. in color. |
| Sprache | Englisch |
