Prostate cancer is not only the most common genitourinary tumor but, accord ing to the tumor registry of Munich, the male tumor with the highest inci dence. The wide range of information concerning this important disease has been dealt with comprehensively. In a time when interested urologists can surf in the internet to find an article they are looking for, they usually get lost because of the flood of papers covering the same subject. Furthermore, they are still alone in deciding which scientific contribution to believe and which will serve their patients best. A well-edited book such as this, however, provi des quick access to all pertinent questions. These renowned authors have taken on the responsibility of writing a balanced report and producing a sort of a guideline, i. e. , a diagnostic or therapeutic standard. The editors are to be congratulated on mastering such a formidable task, bringing together the leading names in prostate cancer to present their views on all the questions one might have about this disease. I trust that this book will serve urologists in practice and their patients well. J. E. Altwein Miinchen Contents Pathology and Molecular Biology of Prostate Cancer 1 Morphogenetic Aspects of Prostate Cancer H. Bonkhoff . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3 2 Cytogenetics of Prostate Cancer L. Bubendorf . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 13 3 Molecular Dissection of the Prostate Cancer Genome V. Srikantan, S. Srivastava . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 25 Diagnosis and Clinical Significance of Prostatic 4 Intraepithelial Neoplasia V. Ravery, L. Boccon-Gibod . . . . . . . . . . . . . . . . . . . . . . . . . . . . .. .

Pathology and Molecular Biology of Prostate Cancer

1 Morphogenetic Aspects of Prostate Cancer
2 Cytogenetics of Prostate Cancer
3 Molecular Dissection of the Prostate Cancer Genome
4 Diagnosis and Clinical Significance of Prostatic Intraepithelial Neoplasia
Diagnosis and Staging of Prostate Cancer
5 Prostate Biopsy - When, How, and When to Repeat?
6 Molecular Forms of Prostate-Specific Antigen for Prostate Cancer Detection
7 Clinical and Pathohistological Prognosticators
8 Preoperative Staging
9 Preoperative Staging of Prostate Cancer: The Role of Molecular Markers
10 Preoperative Imaging Techniques in Prostate Cancer
11 Extended Pelvic Lymphadenectomy in Clinically Localized Prostate Cancer: High Frequency of Lymph Node Metastases
Operative Therapy of Clinically Localized Prostate Cancer
12 Anatomy: Surgical Aspects
13 Extended Pelvic Lymphadenectomy
14 Radical Ascending Retropubic Prostatectomy
15 Radical Descending Retropubic Prostatectomy
16 Radical Retropubic Nerve Sparing Prostatectomy
17 Perineal Prostatectomy
18 Penile Prosthesis Implantation
19 Artificial Urinary Sphincter Implantation
Radiotherapy for Localized Prostate Cancer
20 Radiation Therapy of Prostate Cancer
21 Brachytherapy of Localized Prostate Cancer
Complications Following Radical Prostatectomy
22 Quality of Life Following Radical Prostatectomy
23 Diagnosis and Therapy of Erectile Dysfunction Following Radical Prostatectomy
24 Diagnosis and Therapy of Urinary Stress Incontinence Following Radical Prostatectomy
Therapy of Advanced Prostate Cancer
25 Is Radical Lymphadenectomy Indicated in Lymph Node-Positive Disease?
26 Hormone Therapy for Prostate Cancer
27 Therapeutic Options in Hormone Refractory Prostate Cancer.