It is well known that the CNS is normally protected from immune effectors because of the potential of irreversible damage to the nervous tissue. Nevertheless, there are situations where immune responses occur in the CNS due to different disease processes. Some of these responses are purely pathogenic while others clear or contain disease causing pathogens. In this volume, the mechanisms responsible for the varied outcomes are compared and contrasted.

List of Contents

Hierarchy of Immune Responses to Antigen in the Normal Brain
Cytokines and Chemokines as Mediators of Protection and Injury in the Central Nervous System Assessed in Transgenic Mice
Cytokines in Degenerative Brain Diseases: Lessons from Transgenic Animals
Innate Immune Responses in Viral Encephalitis
Apoptosis in Viral Infections of Neurons: a Protective or Pathologic Host Response?
Markers of Central Nervous System Glia and Neurons In Vivo During Normal and Pathological Conditions
The Role of T Cells in Brain Pathology
Immunopathology and Immunoprotection in CNS Virus Infections: Mechanisms of Virus Clearance from the CNS
HIV-1 and the Central Nervous System
HTLV-1-Mediated Immunopathological CNS Disease
Listeria monocytogenes: a Model System to Study Invasion and Spread of Bacteria in the Central Nervous System
Parasites and the Brain: Neuroinvasion, Immunopathogenesis and Neuronal Dysfunctions
Immune Responses in Glioblastoma: an Avenue to Effective Cancer Therapy or a Mere Epiphenomenon?.