This book, written by authors with national and international reputations in the field, covers all aspects of radionuclide and hybrid bone imaging. Introductory sections present the basic science and consider the current status and limitations of conventional radiological techniques. The underlying principles of PET-CT and SPECT-CT are carefully explained, and the value of different PET and SPECT tracers, assessed. The role of single- and dual-modality approaches in the imaging of benign bone diseases and malignancies is then discussed in detail in a series of well-illustrated chapters. The pathologies addressed include metabolic bone disease, arthritis, bone and joint infections, primary bone and soft tissue tumors, and metastases from breast and prostate cancer. A further section considers the role of bone scintigraphy in the pediatric patient, and the closing chapters focus on miscellaneous subjects, including bone densitometry and radionuclide targeted therapy.

From the contents: Anatomy of skeletal system

Physiology of bone formation, remodelling and metabolism
Pathophysiology of bone metastases
Skeletal tracer kinetics
Biochemical markers in bone diseases
Plain radiography in benign bone disease and bone metastases
CT in benign bone disease and bone metastases
MRI in benign bone disease and bone metastases.-Basic principles of SPECT-CT and PET-CT technology
Bone scintigraphy: SPECT and PET tracers
Current applications and limitations of SPECT
Bone scintigraphy: procedure, variants, artefacts and pitfalls
Bone scintigraphy in metabolic bone disease
Bone scintigraphy in arthritis
SPECT and PET in bone infections
SPECT and PET in joint infections
SPECT-CT in ankle and foot pathology
SPECT-CT in wrist registration
Potential applications and limitations of SPECT-CT in benign bone disease
Bone scintigraphy in trauma
Prostate cancer: role of SPECT and PET in imaging bone metastases
Breast Cancer: role of SPECT and PET in imaging bone metastases.