Numerous diseases in the areas of orthopaedics, rheumatology, and radiology can only be completely diagnosed if the corresponding conditions of the skin and mucous membranes are included in the diagnostic work-up (skin-bone). Conversely, dermatologic assessment of skin symptoms in isolation may lead to serious delays and errors in the diagnosis and treatment of associated changes in the musculoskeletal system. This monograph gives an interdisciplinary synopsis, from a dermatologic and clinical radiologic perspective, of 85 disease entities which in practice are likley to present. For orientation purposes the main dermatologic and radiologic symptoms are presented in table form at the beginning of the book.

Tables of Differential Diagnoses

1 Congenital Disorders1 and Developmental Anomalies
1.1 Nail-Patella Syndrome
1.2 Enchondromatosis with Cavernous Hemangiomas (e.g., Maffucci's Syndrome)
1.3 Fibroosseous Lesions with Café-au-lait Spots
1.4 Neurofibromatosis Type 1
1.5 Tuberous Sclerosis
1.6 Osteopoikilosis with Dermatofibrosis Lenticularis Disseminata and Other Cutaneous Lesions
1.7 Osteopathia Striata and Other Skeletal Malformations with Focal Cutaneous Hypoplasia or Cutaneous Atrophy (e.g., Goltz-Gorlin Syndrome)
1.8 Melorheostosis with Circumscribed Scleroderma
1.9 Gardner's Syndrome
1.10 Cronkhite-Canada Syndrome
1.11 Proteus Syndrome
1.12 Basal Cell Nevus Syndrome (Gorlin-Goltz Syndrome)
1.13 Ichthyosis with Chondrodysplasia Punctata (Conradi-Hünermann Syndrome, Happle's Syndrome)
1.14 Congenital Ichthyosiform Erythroderma with Acro-osteolysis
1.15 Refsum's Syndrome
1.16 Hereditary Palmoplantar Keratosis with Drumstick Fingers and Bony Hypertrophy
1.17 Mutilating Palmoplantar Keratoderma
1.18 Epidermolysis Bullosa Dystrophica with Acro-osteolysis
1.19 Rothmund-Thomson Syndrome
1.20 Werner's Syndrome
1.21 Ehlers-Danlos Syndrome
1.22 Metaphyseal Chondrodysplasia with Complete Alopecia
1.23 Satoyoshi's Syndrome
1.24 Gaucher's Disease
1.25 Fabry's Disease
1.26 Congenital Copper Deficiency
2 Collagen Diseases
2.1 Progressive Systemic Sclerosis (PSS)
2.2 Systemic Lupus Erythematosus (SLE)
2.3 Polymyositis and Dermatomyositis
2.4 Sjögren's Syndrome
2.5 Jo-1 (Antisynthetase) Syndrome
2.6 Sharp's Syndrome
2.7 Undifferentiated Inflammatory Systemic Connective Tissue Disease
3 Rheumatic Disorders
3.1 Rheumatoid Arthritis
3.2 Fibroblastic Rheumatism
3.3 Gouty Arthritis
3.4Hemochromatosis
3.5 Relapsing Polychondritis (RP)
3.6 Seronegative Spondyloarthropathies
3.7 Other Forms of Reactive Arthritis
3.8 Behçet's Syndrome
3.9 Acne-Associated Skeletal Changes
4. Infectious Diseases
4.1 Leprosy
4.2 Syphilis
4.3 Actinomycosis
4.4 Mycetoma
4.5 Bacillary (Epitheloid) Angiomatosis in AIDS
5 Neoplastic and Granulomatous Diseases
5.1 Lymphoma
5.2 Mycosis Fungoides
5.3 POEMS Plasmacytoma
5.4 Langerhans Cell Histiocytosis
5.5 Multicentric Reticulohistiocytosis (MR)
5.6 Sarcoidosis
5.7 Mastocytosis
6 Angiodysplastic Skin Lesions and Skeletal Changes
6.1 Congenital Angiodysplasias
6.2 Acquired Angiodysplasias
7 Periostoses
7.1 Pachydermoperiostosis
7.2 EMO Syndrome
7.3 Hypertrophic Osteoarthropathy
7.4 Periosteal Ossification in Varicose Symptom Complex
7.5 Scurvy
8 Other Diseases
8.1 Nonsystemic Trophic Disorders of the Hands and Feet with Acro-osteolysis
8.2 Sudeck's Syndrome
8.3 Lipoatrophic Diabetes Mellitus
8.4 Pancreatitic Bone Lesions
8.5 Interstitial Calcinosis
8.6 Chromium and Nickel Allergy Due to Internal Fixation Material.