Science of Synthesis: Houben-Weyl Methods of Molecular Transformations is the entirely new edition of the acclaimed reference series Houben-Weyl, the standard synthetic chemistry resource since 1909. This new edition is published in English and will comprise 48 volumes published between the years 2000 and 2008.

Science of Synthesis is a quality reference work developed by a highly esteemed editorial board to provide a comprehensive and critical selection of reliable organic and organometallic synthetic methods. This unique resource is designed to be the first point of reference when searching for a synthesis strategy.

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1;Science of Synthesis - Volume 33: Ene--X Compounds (X = S, Se, Te, N, P);1 1.1;Title page;3 1.2;Imprint;5 1.3;Preface;6 1.4;Volume Editor's Preface;8 1.5;Overview;10 1.6;Table of Contents;14 1.7;Introduction;44 1.8;33.1 Product Class 1: Alk-1-enyl Sulfur Compounds;56 1.8.1;33.1.1 Product Subclass 1: Alk-1-enesulfonic Acids and Derivatives;56 1.8.1.1;33.1.1.1 Synthesis of Product Subclass 1;56 1.8.1.1.1;33.1.1.1.1 Method 1: Synthesis from 2-Chloroalkanesulfonic Acid Derivatives;56 1.8.1.1.2;33.1.1.1.2 Method 2: Condensations of the Carbanions of Sulfonic Acid Derivatives with Carbonyl Compounds;57 1.8.1.1.2.1;33.1.1.1.2.1 Variation 1: Aldol-Type Condensations and Related Processes;57 1.8.1.1.2.2;33.1.1.1.2.2 Variation 2: Wadsworth--Emmons Alkenation Reactions;58 1.8.1.1.3;33.1.1.1.3 Method 3: Cyclic Alk-1-enesulfonic Esters and Sulfonamides by Metathesis Reactions;59 1.8.1.1.4;33.1.1.1.4 Methods 4: Miscellaneous Syntheses of Alk-1-enesulfonic Acid Derivatives from Other Sulfur Compounds;60 1.8.2;33.1.2 Product Subclass 2: Alk-1-enyl Sulfones;62 1.8.2.1;33.1.2.1 Synthesis of Product Subclass 2;62 1.8.2.1.1;33.1.2.1.1 Method 1: Sulfonylation of Nucleophilic Alkenyl Reagents;62 1.8.2.1.2;33.1.2.1.2 Method 2: Condensation of Sulfonyl Carbanions with Carbonyl Compounds;63 1.8.2.1.2.1;33.1.2.1.2.1 Variation 1: Aldol-Type Condensation and Dehydration;63 1.8.2.1.2.2;33.1.2.1.2.2 Variation 2: Knoevenagel Condensation of Activated Sulfones;65 1.8.2.1.2.3;33.1.2.1.2.3 Variation 3: Condensation of Sulfinyl(sulfonyl)methanes with Aldehydes;66 1.8.2.1.2.4;33.1.2.1.2.4 Variation 4: Horner--Wadsworth--Emmons Alkenation of a-Sulfonyl Phosphonates;67 1.8.2.1.2.5;33.1.2.1.2.5 Variation 5: Peterson Alkenation of a-Silylalkyl Sulfones;69 1.8.2.1.3;33.1.2.1.3 Method 3: Sulfonylation of Alkenes Followed by Elimination;71 1.8.2.1.3.1;33.1.2.1.3.1 Variation 1: Chlorosulfenylation of Alkenes, Followed by Sulfur Oxidation and Elimination;71 1.8.2.1.3.2;33.1.2.1.3.2 Variation 2: Sulfonomercuration of Alkenes Followed by Demercuration;72 1.8.2.1.3.3;33.1.2.1.3.3 Variation 3: Selenosulfonylation of Alkenes Followed by Selenium Oxidation;73 1.8.2.1.3.4;33.1.2.1.3.4 Variation 4: Iodosulfonylation of Alkenes Followed by Dehydroiodination;74 1.8.2.1.4;33.1.2.1.4 Method 4: Sulfonylation of Alkynes;76 1.8.2.1.5;33.1.2.1.5 Method 5: Functionalization of Alk-1-ynyl Sulfones;77 1.8.2.1.5.1;33.1.2.1.5.1 Variation 1: Addition Reactions;78 1.8.2.1.5.2;33.1.2.1.5.2 Variation 2: Cycloaddition Reactions;80 1.8.2.1.6;33.1.2.1.6 Method 6: Oxidation of Alk-1-enyl Sulfides and Sulfoxides;80 1.8.2.1.7;33.1.2.1.7 Method 7: Functionalization of Allyl Sulfones and Derivatives;81 1.8.2.1.8;33.1.2.1.8 Method 8: Functionalization of Simple Alk-1-enyl Sulfones;83 1.8.2.1.8.1;33.1.2.1.8.1 Variation 1: a-Functionalization;83 1.8.2.1.8.2;33.1.2.1.8.2 Variation 2: Heck Reaction;85 1.8.2.1.8.3;33.1.2.1.8.3 Variation 3: Cross-Metathesis Reactions;86 1.8.2.1.8.4;33.1.2.1.8.4 Variation 4: Diels--Alder Reactions of Dienyl Sulfones;87 1.8.2.1.8.5;33.1.2.1.8.5 Variation 5: Substitution of ß-Functionalized Alk-1-enyl Sulfones;88 1.8.3;33.1.3 Product Subclass 3: S-Alk-1-enylsulfoximides;94 1.8.3.1;33.1.3.1 Synthesis of Product Subclass 3;94 1.8.3.1.1;33.1.3.1.1 Method 1: Condensation of Sulfonimidoyl Carbanions with Carbonyl Compounds;94 1.8.3.1.1.1;33.1.3.1.1.1 Variation 1: Aldol-Type Condensations of a-Sulfonimidoyl Carbanions and the Dehydration of the Intermediate ß-Hydroxylated Sulfoximides;95 1.8.3.1.1.2;33.1.3.1.1.2 Variation 2: Peterson and Wadsworth--Emmons Alkenation Reactions;97 1.8.3.1.2;33.1.3.1.2 Method 2: Imination of Alk-1-enyl Sulfoxides;98 1.8.3.1.3;33.1.3.1.3 Method 3: Functionalization of Simple S-Alk-1-enyl- and S-Alk-2-enylsulfoximides;99 1.8.4;33.1.4 Product Subclass 4: Alk-1-enesulfinic Acids and Derivatives;102 1.8.4.1;33.1.4.1 Synthesis of Product Subclass 4;102 1.8.4.1.1;33.1.4.1.1 Method 1: Reaction of Allenes and Alkynes