Science of Synthesis: Houben-Weyl Methods of Molecular Transformations is the entirely new edition of the acclaimed reference series Houben-Weyl, the standard synthetic chemistry resource since 1909. This new edition is published in English and will comprise 48 volumes published between the years 2000 and 2008.

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1;Science of Synthesis - Volume 47a: Alkenes;1 1.1;Title page;3 1.2;Imprint;5 1.3;Preface;6 1.4;Volume Editor's Preface;8 1.5;Overview;10 1.6;Table of Contents;12 1.7;Introduction;22 1.8;47.1 Product Class 1: Alkenes;30 1.8.1;47.1.1 Synthesis by Alkenation Reactions;30 1.8.1.1;47.1.1.1 Wittig and Related Phosphorus-Based Alkenations;30 1.8.1.1.1;47.1.1.1.1 Monosubstituted Alkenes;31 1.8.1.1.1.1;47.1.1.1.1.1 Method 1: Synthesis from Aldehydes and Methylenetriphenylphosphorane;31 1.8.1.1.1.1.1;47.1.1.1.1.1.1 Variation 1: Wittig Alkenation with Methylenetriphenylphosphorane Generated In Situ;33 1.8.1.1.1.1.2;47.1.1.1.1.1.2 Variation 2: Wittig Alkenation with Methylenetriphenylphosphorane and Aldehyde Generated In Situ;36 1.8.1.1.1.1.3;47.1.1.1.1.1.3 Variation 3: Wittig Alkenation under Phase-Transfer Conditions;38 1.8.1.1.1.1.4;47.1.1.1.1.1.4 Variation 4: Synthesis of 13C- and 2H-Labeled Terminal Alkenes from Labeled Methyltriphenylphosphonium Halides;39 1.8.1.1.1.2;47.1.1.1.1.2 Method 2: Synthesis from Formaldehyde and Alkylidenetriphenylphosphoranes;41 1.8.1.1.2;47.1.1.1.2 1,1-Disubstituted Alkenes;43 1.8.1.1.2.1;47.1.1.1.2.1 Method 1: Synthesis from Ketones and Methylenetriphenylphosphorane;43 1.8.1.1.2.2;47.1.1.1.2.2 Method 2: Synthesis from Formaldehyde and Alkylidenetriphenylphosphoranes;47 1.8.1.1.2.2.1;47.1.1.1.2.2.1 Variation 1: Wittig Alkenation with Preformed Ylides and Formaldehyde in Aqueous Solution;47 1.8.1.1.2.2.2;47.1.1.1.2.2.2 Variation 2: Wittig Alkenation with Paraformaldehyde and Ylides Formed In Situ;48 1.8.1.1.3;47.1.1.1.3 Z-1,2-Disubstituted Alkenes;48 1.8.1.1.3.1;47.1.1.1.3.1 Method 1: Wittig Alkenation of Preformed Stable Aldehydes;49 1.8.1.1.3.1.1;47.1.1.1.3.1.1 Variation 1: Reaction under Homogeneous Conditions;49 1.8.1.1.3.1.2;47.1.1.1.3.1.2 Variation 2: Reaction with Immobilized Ylides;51 1.8.1.1.3.1.3;47.1.1.1.3.1.3 Variation 3: Reaction under Phase-Transfer Conditions;53 1.8.1.1.3.2;47.1.1.1.3.2 Method 2: Wittig Alkenation of Aldehydes Prepared In Situ;54 1.8.1.1.3.2.1;47.1.1.1.3.2.1 Variation 1: Alkenation of Aldehydes Prepared In Situ by Oxidation of Alcohols;54 1.8.1.1.3.2.2;47.1.1.1.3.2.2 Variation 2: Alkenation of Aldehydes Prepared In Situ by Reduction;58 1.8.1.1.3.2.3;47.1.1.1.3.2.3 Variation 3: Alkenation of Aldehydes Prepared by Oxidation of Ylides or Alkenes;61 1.8.1.1.3.2.4;47.1.1.1.3.2.4 Variation 4: Alkenation of Masked Aldehydes;62 1.8.1.1.3.3;47.1.1.1.3.3 Method 3: Alkenation with (Triphenylphosphoranylidene)alkanoates and -alkoxides;64 1.8.1.1.3.3.1;47.1.1.1.3.3.1 Variation 1: Ylide Generation with an Excess of Base;64 1.8.1.1.3.3.2;47.1.1.1.3.3.2 Variation 2: Alkenation with In Situ Silylated Alkoxide Ylides;66 1.8.1.1.3.4;47.1.1.1.3.4 Method 4: Z-Selective Wittig--Horner Alkenation;67 1.8.1.1.4;47.1.1.1.4 E-1,2-Disubstituted Alkenes;70 1.8.1.1.4.1;47.1.1.1.4.1 Method 1: The Schlosser Modification of the Wittig Alkenation;70 1.8.1.1.4.2;47.1.1.1.4.2 Method 2: E-Selective Wittig--Horner Alkenation;71 1.8.1.1.4.3;47.1.1.1.4.3 Method 3: E-Selective Alkenation with Ylides Bearing Substitutents Other Than Triphenylphosphine;73 1.8.1.1.5;47.1.1.1.5 Tri- and Tetrasubstituted Alkenes;75 1.8.1.1.5.1;47.1.1.1.5.1 Method 1: Non-Stereocontrolled Wittig Alkenations;75 1.8.1.1.5.1.1;47.1.1.1.5.1.1 Variation 1: Synthesis with Symmetrical Phosphoranes or Ketones;75 1.8.1.1.5.1.2;47.1.1.1.5.1.2 Variation 2: Synthesis with (Cycloalkylidene)triphenylphosphoranes;77 1.8.1.1.5.1.3;47.1.1.1.5.1.3 Variation 3: Synthesis with Unsymmetrical Phosphorus Ylides and Unsymmetrical Ketones;79 1.8.1.1.5.2;47.1.1.1.5.2 Method 2: Stereocontrolled Alkenations;82 1.8.1.1.5.2.1;47.1.1.1.5.2.1 Variation 1: The SCOOPY Procedure;82 1.8.1.1.5.2.2;47.1.1.1.5.2.2 Variation 2: With Phosphole-Derived Ylides;83 1.8.1.1.5.2.3;47.1.1.1.5.2.3 Variation 3: Horner--Emmons and Wittig--Horner Alkenations with Phosphonates and Phosphine Oxides;85 1.8.1.1.5.2.4;47.1.1.1.5.2.4 Variation 4: Indi