Science of Synthesis: Houben-Weyl Methods of Molecular Transformations is the entirely new edition of the acclaimed reference series Houben-Weyl, the standard synthetic chemistry resource since 1909. This new edition is published in English and will comprise 48 volumes published between the years 2000 and 2008.

Science of Synthesis is a quality reference work developed by a highly esteemed editorial board to provide a comprehensive and critical selection of reliable organic and organometallic synthetic methods. This unique resource is designed to be the first point of reference when searching for a synthesis strategy.

• Contains the expertise of presently 400 leading chemists worldwide
• Critically evaluates the preparative applicability and significance of the synthetic methods
• Discusses relevant background information and provides detailed experimental procedures

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1;Science of Synthesis - Volume 47b: Alkenes;1 1.1;Title page;3 1.2;Imprint;5 1.3;Preface;6 1.4;Volume Editor's Preface;8 1.5;Overview;10 1.6;Table of Contents;12 1.7;47.1 Product Class 1: Alkenes;24 1.7.1;47.1.3 Synthesis by Pericyclic Reactions;24 1.7.1.1;47.1.3.1 Diels--Alder Reactions;24 1.7.1.1.1;47.1.3.1.1 Thermal Diels--Alder Reactions;42 1.7.1.1.1.1;47.1.3.1.1.1 Method 1: Reactions of Carbonyl Dienophiles;42 1.7.1.1.1.1.1;47.1.3.1.1.1.1 Variation 1: Synthesis of Cyclohexenecarbaldehydes;42 1.7.1.1.1.1.2;47.1.3.1.1.1.2 Variation 2: Synthesis of Acetylcyclohexenes;48 1.7.1.1.1.1.3;47.1.3.1.1.1.3 Variation 3: Synthesis of Cyclohexenecarboxylic Acids and Alkyl Cyclohexenecarboxylates;54 1.7.1.1.1.1.4;47.1.3.1.1.1.4 Variation 4: Synthesis of Dialkyl Cyclohexenedicarboxylates;60 1.7.1.1.1.1.5;47.1.3.1.1.1.5 Variation 5: Synthesis of Cyclohexenecarboxylic Acids, Cyclohexene carbonyl Chlorides, Cyclohexenecarboxamides, and Cyclohexenyl Silyl Ketones;64 1.7.1.1.1.1.6;47.1.3.1.1.1.6 Variation 6: Synthesis of Cyclohexenes Fused to Carbo- and Heterocycles;67 1.7.1.1.1.1.7;47.1.3.1.1.1.7 Variation 7: Synthesis of Bridged Cyclohexenes;82 1.7.1.1.1.2;47.1.3.1.1.2 Method 2: Reactions of Other Vinyl Dienophiles;94 1.7.1.1.1.2.1;47.1.3.1.1.2.1 Variation 1: Synthesis of Nitrocyclohexenes;94 1.7.1.1.1.2.2;47.1.3.1.1.2.2 Variation 2: Synthesis of Cyclohexenylboranes;97 1.7.1.1.1.2.3;47.1.3.1.1.2.3 Variation 3: Synthesis of Cyclohexenecarbonitriles;101 1.7.1.1.1.2.4;47.1.3.1.1.2.4 Variation 4: Synthesis of Cyclohex-3-enyl Phenyl Sulfones;104 1.7.1.1.1.2.5;47.1.3.1.1.2.5 Variation 5: Synthesis of (Hydroxyalkyl)cyclohexenes;107 1.7.1.1.1.2.6;47.1.3.1.1.2.6 Variation 6: Synthesis of Cyclohexenes from Unusual Dienophiles;111 1.7.1.1.1.3;47.1.3.1.1.3 Method 3: Synthesis of Cyclohexenyl-Substituted Fischer Carbene Complexes;114 1.7.1.1.1.4;47.1.3.1.1.4 Method 4: Synthetic Applications of Diels--Alder Reactions;118 1.7.1.1.2;47.1.3.1.2 Catalyzed Diels--Alder Reactions in Conventional Organic Media;123 1.7.1.1.2.1;47.1.3.1.2.1 Method 1: Reactions Using Classic Lewis Acid Catalysts;125 1.7.1.1.2.2;47.1.3.1.2.2 Method 2: Reactions Using Chiral Lewis Acid Catalysts;134 1.7.1.1.2.3;47.1.3.1.2.3 Method 3: Reactions Using Brønsted Acid Catalysts;138 1.7.1.1.2.4;47.1.3.1.2.4 Method 4: Reactions Using Chiral Organocatalysts;142 1.7.1.1.2.5;47.1.3.1.2.5 Method 5: Lewis Acid Catalyzed Diels--Alder Reactions of Chiral Dienophiles or Dienes;145 1.7.1.1.2.5.1;47.1.3.1.2.5.1 Variation 1: With Chiral Dienophiles;145 1.7.1.1.2.5.2;47.1.3.1.2.5.2 Variation 2: With Chiral Dienes;150 1.7.1.1.2.6;47.1.3.1.2.6 Method 6: Reactions Using Heterogeneous Catalysts;152 1.7.1.1.3;47.1.3.1.3 Diels--Alder Reactions in Unconventional Media;157 1.7.1.1.3.1;47.1.3.1.3.1 Method 1: Reactions in Water;157 1.7.1.1.3.1.1;47.1.3.1.3.1.1 Variation 1: Without a Catalyst;157 1.7.1.1.3.1.2;47.1.3.1.3.1.2 Variation 2: With a Lewis Acid Catalyst;160 1.7.1.1.3.1.3;47.1.3.1.3.1.3 Variation 3: With Organocatalysts;163 1.7.1.1.3.1.4;47.1.3.1.3.1.4 Variation 4: In Supercritical Water;164 1.7.1.1.3.1.5;47.1.3.1.3.1.5 Variation 5: In Pseudo-Biological Systems or Promoted by Biocatalysts;165 1.7.1.1.3.2;47.1.3.1.3.2 Method 2: Reactions in Nonaqueous Solvents and Their Salt Solutions;167 1.7.1.1.3.3;47.1.3.1.3.3 Method 3: Reactions in Ionic Liquids;170 1.7.1.1.4;47.1.3.1.4 Diels--Alder Reactions Induced by Other Physical Means;175 1.7.1.1.4.1;47.1.3.1.4.1 Method 1: Diels--Alder Reactions Promoted by Microwave Irradiation;175 1.7.1.1.4.2;47.1.3.1.4.2 Method 2: Diels--Alder Reactions Promoted by High Pressure;178 1.7.1.1.4.3;47.1.3.1.4.3 Method 3: Ultrasound-Assisted Diels--Alder Reactions;182 1.7.1.1.4.4;47.1.3.1.4.4 Method 4: Photoinduced Diels--Alder Reactions;185 1.7.1.2;47.1.3.2 Ene Reactions;200 1.7.1.2.1;47.1.3.2.1 Method 1: Thermal Ene Reactions;202 1.7.1.2.1.1;47.1.3.2.1.1 Variation 1: Intermolecular Ene Reactions;202 1.7.1.2.1.2;47.1.3.2.1.2 Vari