The Science of Synthesis Editorial Board, together with the volume editors and authors, is constantly reviewing the whole field of synthetic organic chemistry as presented in Science of Synthesis and evaluating significant developments in synthetic methodology. Several annual volumes updating content across all categories ensure that you always have access to state-of-the-art synthetic methodology.

1;Science of Synthesis: Knowledge Updates 2017/2;1 2;Title Page;7 3;Imprint;8 4;Preface;9 5;Abstracts;11 6;Overview;19 7;Table of Contents;21 8;17.9.24 Phthalocyanines and Related Compounds;35 8.1;17.9.24.1 Metal-Free Phthalocyanines;36 8.1.1;17.9.24.1.1 Method 1: Synthesis from Phthalonitrile;37 8.1.2;17.9.24.1.2 Method 2: Synthesis from Bicyclo[2.2.2]octadiene-Fused Tetraazaporphyrins (Porphyrazines);39 8.1.3;17.9.24.1.3 Method 3: Synthesis from Phthalimide, Phthalic Anhydride, or Phthalic Acid;40 8.1.4;17.9.24.1.4 Method 4: Demetalation of a Zinc Complex;42 8.2;17.9.24.2 Metal-Phthalocyanine Complexes;42 8.2.1;17.9.24.2.1 Method 1: Synthesis from Phthalonitrile;43 8.2.2;17.9.24.2.2 Method 2: Synthesis from Phthalic Anhydride;47 8.2.3;17.9.24.2.3 Method 3: Synthesis from Phthalic Acid;49 8.2.4;17.9.24.2.4 Method 4: Synthesis from Phthalimide;49 8.3;17.9.24.3 1,8(11),15(18),22(25)-Tetrasubstituted Phthalocyanines and 1:25,11:15-Bridged Phthalocyanines;51 8.3.1;17.9.24.3.1 Method 1: Synthesis from 3-Substituted Phthalonitriles;51 8.3.1.1;17.9.24.3.1.1 Variation 1: Regioselective Preparation of 1,8,15,22-Tetrasubstituted Phthalocyanines from 3-Substituted Phthalonitriles;51 8.3.2;17.9.24.3.2 Method 2: Side-Strapped 1:25,11:15-Tetrasubstituted Phthalocyanines from Bis (isoindolinediimines);52 8.3.3;17.9.24.3.3 Method 3: Postfunctionalization of Phthalocyanines;53 8.3.3.1;17.9.24.3.3.1 Variation 1: Derivatization of Peripheral Substituents;54 8.3.3.2;17.9.24.3.3.2 Variation 2: Chiral 1,8,15,22-Tetrasubstituted Phthalocyanines;56 8.4;17.9.24.4 2,9(10),16(17),23(24)-Tetrasubstituted Phthalocyanines and 2:24,10:16-Bridged Phthalocyanines;61 8.4.1;17.9.24.4.1 Method 1: Synthesis from 4-Substituted Phthalonitriles;62 8.4.1.1;17.9.24.4.1.1 Variation 1: Side-Strapped 2:24,10:16-Bridged Phthalocyanines from 4,4?-Substituted Bis (phthalonitriles);62 8.4.2;17.9.24.4.2 Method 2: Synthesis from 4-Substituted Phthalic Anhydrides;64 8.4.3;17.9.24.4.3 Method 3: Synthesis from 4-5 Substituted Phthalimides;65 8.4.4;17.9.24.4.4 Method 4: Derivatization of Peripheral Substituents;65 8.4.5;17.9.24.4.5 Method 5: Postfunctionalization of Axial Substituents;67 8.5;17.9.24.5 1,3,8,10(9,11),15,17(16,18),22,24(23,25)-Octasubstituted Phthalocyanines;68 8.5.1;17.9.24.5.1 Method 1: Synthesis from 3,5-Disubstituted Phthalic Acids;68 8.5.2;17.9.24.5.2 Method 2: Postfunctionalization of Phthalocyanines;69 8.6;17.9.24.6 1,4,8,11,15,18,22,25-Octasubstituted Phthalocyanines;71 8.6.1;17.9.24.6.1 Method 1: Synthesis from 3,6-Disubstituted Phthalonitriles;71 8.6.2;17.9.24.6.2 Method 2: Derivatization of Peripheral Substituents;73 8.6.3;17.9.24.6.3 Method 3: Postfunctionalization of Axial Substituents;73 8.7;17.9.24.7 2,3,9,10,16,17,23,24-Octasubstituted Phthalocyanines;75 8.7.1;17.9.24.7.1 Method 1: Synthesis from 4,5-Disubstituted Phthalonitriles;75 8.7.1.1;17.9.24.7.1.1 Variation 1: Octasubstituted Phthalocyanines Possessing Two Types of Substituents;77 8.7.2;17.9.24.7.2 Method 2: Synthesis from 4,5-Disubstituted Phthalic Anhydrides;79 8.7.3;17.9.24.7.3 Method 3: Synthesis from 5,6-Disubstituted Isoindoline-1,3-diimines;79 8.7.4;17.9.24.7.4 Method 4: Derivatization of Peripheral Substituents;80 8.7.5;17.9.24.7.5 Method 5: Postfunctionalization of Axial Substituents;82 8.8;17.9.24.8 2:3,9:10,16:17,23:24-Bridged Phthalocyanines;84 8.8.1;17.9.24.8.1 Method 1: Synthesis from 4:5-Bridged Phthalonitriles;84 8.8.2;17.9.24.8.2 Method 2: Synthesis from 5:6-Bridged Isoindoline-1,3-diimines;86 8.8.3;17.9.24.8.3 Method 3: Synthesis from 5:6-Bridged Phthalic Anhydrides;87 8.8.4;17.9.24.8.4 Method 4: Derivatization of Peripheral Substituents;88 8.9;17.9.24.9 Dodecasubstituted Phthalocyanines;90 8.9.1;17.9.24.9.1 Method 1: Synthesis from 3,4,5-Trisubstituted Phthalonitriles;91 8.9.2;17.9.24.9.2 Method 2: Synthesis from 3,4,5-Trisubstituted Phthalic Acids;92 8.9.3;17.9.24.9.3 Method 3: Synthesis from 3,4,6-Trisubstituted Phthalonitriles;92 8.10;17.9.24.10 1,2,3,4,8,9,10,11,15,16,1