Die "study edition" des erfolgreichen Bandes 102 des "Handbook of Experimental Pharmacology" vermittelt einen umfassenden Überblick über die Topographie und das Verhalten von Neurotoxinen auf molekularer Ebene. Anhand neuester Erkenntnisse auf dem Gebiet der molekularen Neurobiologie werden die Mechanismen der Selektivität der verschiedenen Neurotoxine in verständlicher Weise dargestellt.

Cellular and Subcellular Targets of Neurotoxins: The Concept of Selective Vulnerability

Protective Barriers in the Peripheral Nervous System to Neurotoxic Agents
Protective Barriers in the Nervous System Against Neurotoxic Agents: The Blood-Brain Barrier
Kinetic and Metabolic Disorders of Axoplasmic Transport Induced by Neurotoxic Agents
Metabolic Disorders as Consequences of Drug-Induced Energy Deficits
Neurotoxic Synthesis by Enzymatic Error
Neurotropic Carcinogenesis
Neurotoxic Phenylalkylamines and Indolealkylamines
Toxins Affecting the Cholinergic System
Mechanisms of 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine Induced Destruction of Dopaminergic Neurons
Tetanus and Botulinum Neurotoxins
Capsaicin: Selective Toxicity for Thin Primary Sensory Neurons
Excitotoxins, Glutamate Receptors, and Excitotoxicity
Convulsants and Gamma-Aminobutyric Acid Receptors
Convulsants Acting at the Inhibitory Glycine Receptor
Peptide Toxins Acting on the Nicotinic Acetylcholine Receptor
Nicotinic Acetylcholine Receptors and Low Molecular Weight Toxins
Neurotoxic Agents Interacting with the Muscarinic Acetylcholine Receptor
Peptide Toxins that Alter Neurotransmitter Release
Sodium Channel Specific Neurotoxins: Recent Advances in the Understanding of Their Molecular Mechanisms
Potassium Channel Toxins
Calcium Channel Toxins
ADP-Ribosylation of Signal-Transducing Guanine Nucleotide Binding Proteins by Cholera and Pertussis Toxin
Clostridium botulinum C2 Toxin and C. botulinum C3 ADP-Ribosyltransferase.