Stereotactic body radiation therapy (SBRT) has emerged as an important innovative treatment for various primary and metastatic cancers. This book provides a comprehensive and up-to-date account of the physical/technological, biological, and clinical aspects of SBRT. It will serve as a detailed resource for this rapidly developing treatment modality. The organ sites covered include lung, liver, spine, pancreas, prostate, adrenal, head and neck, and female reproductive tract. Retrospective studies and prospective clinical trials on SBRT for various organ sites from around the world are examined, and toxicities and normal tissue constraints are discussed. This book features unique insights from world-renowned experts in SBRT from North America, Asia, and Europe. It will be necessary reading for radiation oncologists, radiation oncology residents and fellows, medical physicists, medical physics residents, medical oncologists, surgical oncologists, and cancer scientists.

Introduction

Safety and Quality Assurance
CyberKnife system
Novalis system
HiART TomoTherapy system
Treatment planning
AAPM recommendation
Launching a stereotactic body radiation therapy program
Radiobiology of stereotactic body radiation therapy
Primary Lung Cancer
Primary Liver Cancer
Prostate Cancer
Cell Carcinoma
Gynecologic Cancer
Pancreatic Cancer
Benign and Malignant Primary Spinal Tumors
Non-Skull Base Head and Neck Cancer
Skull Base Head and Neck Cancer
Lung Metastasis
Liver Metastasis
Adrenal Metastasis
Histologic Specific Metastasis
Bone Metastasis
Spinal Metastasis
Reported toxicities associated with stereotactic body radiation therapy
Normal tissue constraints.-Conduction of Trials in Stereotactic Body Radiation Therapy.