Stress Challenges and Immunity in Space
From Mechanisms to Monitoring and Preventive Strategies
E-Book
Stress Challenges and Immunity in Space
From Mechanisms to Monitoring and Preventive Strategies
Stress of either a psychological or a physical nature can activate and/or paralyse humans innate or adaptive immunity. However, adequate immunity is crucial to the maintenance of health on earth and in space. During space flight, human physiology and health are challenged by complex environmental stressors (confinement, gravitation, oxygen tension, radiation) which might be at their most pronounced during lunar or interplanetary missions. This book adopts an interdisciplinary approach in seeking to identify the impact of living conditions in space on the adaptation of the immune system. While other publications have addressed the physiological changes that occur during space flight, to the authors knowledge this is the first book specifically to analyze the complex interaction of living conditions in space, the immune system, and astronauts health. It is explained how such analysis of the consequences of stress for the immune system may help in preventing, diagnosing, and counteracting immune-related alterations in health on earth as well as in space.
From the contents:"Stress & Immunity"-research: a tight link between space and earth
From the contents:"Stress & Immunity"-research: a tight link between space and earth
A personal view from above
A personal view after Antarctic overwintering
A personal view from daily "stressed life"
1 Stress & Immunity
1.1 What is Stress? More than a word
1.2 The Immune System, A circulating organ
2 Stress and Immune homeostasis, from earth to space
2.1 Brain & Neuroendocrine responses
2.1.1 tress, genes and cognitive functions
2.1.2 Glucocorticoids, brain activation and memory
2.1.3 The autonomous nervous system
2.1.4 Endocannabinoids,"new-old" mediators of stress homeostasis
2.1.5 Stress and Pain-control
2.2 Clinical Immunology:
2.2.1 Long duration missions
2.2.2 Stress and Innate Immune Responses
2.2.3 Stress and Adaptive Immune Responses
2.2.4 Purinergic control of innate and adaptive Immunity
2.2.5 Stress and Radiation-responsiveness
2.2.6 Microbiological "load" and Stress resistance in Space
2.2.7 Stress, Spaceflight and Aging
3 Preventive and Therapeutic Strategies: today and tomorrow
3.1 Platforms for Mimicking Space flight on Earth
3.2 Astronaut selection
3.3 Countermeasures
4 Diagnosis: current and future tools (15-20 pages)
4.1 Non-invasive Monitoring
4.2 Minimal invasive Monitoring
5Outlook
5.1Touristic Space flights
5.2Moon, Mars and beyond
Chouker, Alexander
| ISBN | 9783642222726 |
|---|---|
| Artikelnummer | 9783642222726 |
| Medientyp | E-Book - PDF |
| Copyrightjahr | 2011 |
| Verlag | Springer-Verlag |
| Umfang | 469 Seiten |
| Sprache | Englisch |
| Kopierschutz | Adobe DRM |
