1;Structures and Organelles in Pathogenic Protists;3 1.1;Preface;5 1.2;Reference;6 1.3;Contents;7 1.4;Contributors;9 1.5;The Mastigont System in Trichomonads;13 1.5.1;1 Introduction;14 1.5.2;2 The Mastigont System;14 1.5.2.1;2.1 Basal Bodies and Associated Filaments;16 1.5.2.1.1;2.1.1 Basal Body (kinetosomes);16 1.5.2.1.2;2.1.2 Kinetosome R;18 1.5.2.1.3;2.1.3 Kinetosomes #1, #2, #3, #4;18 1.5.2.1.4;2.1.4 Clockwise Filaments;19 1.5.2.1.5;2.1.5 Sigmoidal Filaments;20 1.5.2.1.6;2.1.6 Supra-Kinetosomal Body or Supra-Basal Body;21 1.5.2.1.7;2.1.7 Infra-Kinetosomal Body or Infra-Basal Body;23 1.5.2.1.8;2.1.8 Marginal Lamella;23 1.5.2.2;2.2 Costa;23 1.5.2.2.1;2.2.1 Structure;23 1.5.2.2.2;2.2.2 Types of Costa;24 1.5.2.2.3;2.2.3 Association with Other Structures;24 1.5.2.2.4;2.2.4 Function and Motility;25 1.5.2.2.5;2.2.5 Chemical Composition;25 1.5.2.3;2.3 Comb;25 1.5.2.4;2.4 Axostyle and Pelta;26 1.5.2.4.1;2.4.1 Structure;26 1.5.2.4.2;2.4.2 Pelta;28 1.5.2.4.3;2.4.3 Functions;29 1.5.2.4.4;2.4.4 Stability;29 1.5.2.4.5;2.4.5 Movement;29 1.5.2.4.6;2.4.6 Composition;29 1.5.2.4.7;2.4.7 Association with Other Cell Structures;30 1.5.2.5;2.5 The Parabasal Filaments;30 1.5.2.6;2.6 Flagella;30 1.5.2.6.1;2.6.1 The Undulating Membrane;31 1.5.2.6.2;2.6.2 Flagellar Structure;31 1.5.2.6.3;2.6.3 Flagellar Movement;32 1.5.2.6.4;2.6.4 Flagellum Internalisation;33 1.5.3;3 The Spindle;33 1.5.3.1;3.1 The Atractophore;33 1.5.4;4 Centrin;35 1.5.5;5 Genome Sequence;36 1.5.6;References;36 1.6;Subpellicular Microtubules in Apicomplexa and Trypanosomatids;39 1.6.1;1 Introduction;6 1.6.2;2 Subpellicular Microtubules;41 1.6.2.1;2.1 In Trypanosomatids;42 1.6.2.2;2.2 In Apicomplexans;43 1.6.3;3 Visualization of the Whole Network of Subpellicular Microtubules;44 1.6.3.1;3.1 In Trypanosomatids;45 1.6.3.2;3.2 In Apicomplexans;45 1.6.4;4 High-Resolution Images of the Microtubules;49 1.6.4.1;4.1 In Trypanosomatids;49 1.6.4.2;4.2 In Apicomplexa;50 1.6.5;5 Immunocytochemical Characterization of the Microtubules;51 1.6.5.1;5.1 In Trypanosomatids;53 1.6.5.2;5.2 In Apicomplexa;55 1.6.6;6 Biochemistry;56 1.6.6.1;6.1 In Trypanosomatids;56 1.6.7;7 Drug Sensitivity;57 1.6.7.1;7.1 In Trypanosomatids;58 1.6.7.2;7.2 In Apicomplexa;58 1.6.8;8 Microtubule-Microtubule and Microtubule-Plasma Membrane Associations;58 1.6.8.1;8.1 In Trypanosomatids;59 1.6.8.2;8.2 In Apicomplexa;59 1.6.8.3;8.3 The Conoid in Apicomplexa;60 1.6.9;9 In Trypanosomatids;64 1.6.10;10 In Apicomplexans;64 1.6.11;11 Functional Data;65 1.6.11.1;11.1 In Trypanosomatids;66 1.6.11.2;11.2 In Apicomplexans;66 1.6.12;12 Perspectives;67 1.6.13;References;68 1.7;Flagellum Structure and Function in Trypanosomes;75 1.7.1;1 Introduction;76 1.7.2;2 The Structure of the Flagellum;77 1.7.3;3 The Basal Body;77 1.7.3.1;3.1 The Transition Zone;80 1.7.3.2;3.2 The Axoneme;81 1.7.3.3;3.3 The Paraflagellar Rod;82 1.7.4;4 Flagellar Positioning and Adhesion;83 1.7.5;5 Flagellum Construction;85 1.7.5.1;5.1 Trypanosome Cell Cycle;85 1.7.5.2;5.2 Intraflagellar Transport;89 1.7.6;6 Functions of a Motile Flagellum;91 1.7.6.1;6.1 Characteristics of Flagellum Motility;91 1.7.6.2;6.2 Flagellum Motility Contributes to Completion of Cell Division;92 1.7.6.3;6.3 Motility and Clearance of Surface Proteins;92 1.7.7;7 Conclusions and Perspectives;93 1.7.8;References;94 1.8;The Flagellar Pocket of Trypanosomatids: A Critical Feature for Cell Morphogenesis and Pathogenicity;99 1.8.1;1 Introduction;100 1.8.2;2 Physical Architecture of the Flagellar Pocket;101 1.8.2.1;2.1 New Insights Provided by Electron Tomography;103 1.8.3;3 Physical Organisation of the Flagellar Pocket and Dynamics of Operation;104 1.8.3.1;3.1 Entry of Macromolecules into the Flagellar Pocket: The ``Neck Channel´´;104 1.8.3.2;3.2 Membrane Domains and Boundaries Within the Flagellar Pocket;107 1.8.4;4 The Role of the Flagellar Pocket in Immune Evasion;107 1.8.5;5 Life Cycle Differences in Size and Function of the Flagellar Pocket;109 1.8.6;6 Molecules Associated with the Flagellar Pocke