The History of the TNM System The TNM System for the c1assification of malignant tumours was developed by Pierre Denoix (France) between the years 1943 1 and 1952. In 1950 the UICC appointed a Committee on Thmour Nomen clature and Statistics and adopted, as a basis for its work on clini cal stage c1assification, the general definitions of local extension of malignant tumours suggested by the World Health Organiza tion (WHO) Sub-Committee on The Registration of Cases of 2 Cancer as weIl as their Statistical Presentation. In 1953 the Committee held a joint meeting with the Interna tional Commission on Stage-Grouping in Cancer and Presenta tion of the Results of Treatment of Cancer appointed by the International Congress of Radiology. Agreement was reached on a general technique for c1assification by anatomical extent of dis ease, using the TNM system. In 1954 the Research Comrnission of the UICC set up a spe cial Committee on Clinical Stage Classification and Applied Statis ticsto "pursue studies in this field and to extend the general tech nique of c1assification to cancer at aIl sites". In 1958 the Committee published its first recommendations for the clinical stage classification of cancers of the breast and 1 Denoix, P.F.: BuH. Inst. Nat. Hyg. (Paris) 1: 1-69 (1944) and 5: 52-82 (1944).

Head and Neck Tumours

Lip and Oral Cavity
Pharynx
Larynx
Maxillary Sinus
Salivary Glands
Thyroid Gland
Digestive System Tumours
Oesophagus
Stomach
Colon and Rectum
Anal Canal
Liver
Gall Bladder
Extrahepatic Bile Ducts
Ampulla of Vater
Pancreas
Lung Tumours
Tumours of Bone and Soft Tissues
Bone
Soft Tissue
Skin Tumours
Carcinoma of Skin
Melanoma of Skin
Breast Tumours
Gynaecological Tumours
Cervix Uteri
Corpus Uteri
Ovary
Vagina
Vulva
Urological Tumours
Prostate
Testis
Penis
Urinary Bladder
Kidney
Renal Pelvis and Ureter
Urethra
Ophthalmic Tumours
Carcinoma of Eyelid
Malignant Melanoma of Eyelid
Carcinoma of Conjunctiva
Malignant Melanoma of Conjunctiva
Malignant Melanoma of Uvea
Retinoblastoma
Sarcoma of Orbit
Carcinoma of Lacrimal Gland
Brain Tumours
Hodgkin's Disease
Non-Hodgkin's Lymphoma
Paediatric Tumours
Nephroblastoma (Wilms' Tumour)
Neuroblastoma
Soft Tissue Sarcomas - Paediatric.