This book summarizes the papers presented at the symposium "Dynamics and Regulation of the Arterial System" held at Erlangen on 28-30 October 1977 in honor of Professor Erik Wetterer. The aim of the symposium was an inten sive exchange of ideas within a mUltidisciplinary group of scientists who are specialists in their fields of research. It is obvious that a two-day symposium covering such a wide range of topics could only highlight certain aspects of the latest research on the cardiovascular system. The book is divided into three sections. The first part deals with arterial hemo dynamics. Emphasized are the mechanical properties of the arterial wall, in particular the smooth muscle, fundamental parameters for the description of pulse wave propagation, such as attenuation, phase velocity, and reflection of pulse waves. Furthermore, new methods for recording arterial diameters and the latest results in determining pulsatile pressure and pulsatile diameter of arteries in vivo as well as from calculations based on models of the arterial system are presented. The second part deals with applications of the control theory and the principles of optimality of the cardiovascular system in toto and of single regions of this system. Contributions to research in the field of regulation of blood volume and of regional hemodynamics are also presented. The third part covers problems of interaction of the heart and the arterial system, including fluid mechanics of the aortic valves and the coronary blood flow under normal and pathologic conditions.

Dynamics of the Arterial System

Mechanics of the Arterial Wall in Health and Disease
Prediction of Shape Changes of Propagating Flow and Pressure Pulses in Human Arteries
New Ways of Determining the Propagation Coefficient and the Visco-Elastic Behaviour of Arteries in situ
Arterial Reflection
Arterial Smooth Muscle Mechanics
Models of the Arterial System
Separation of Time-Dependent and Time-Independent Terms in the Relation of Pressure and Diameter and of Pressure and Flow Velocity in Arteries
Determination of the Tangential Elastic Modulus of Human Arteries In Vivo
Model of Nonlinear Viscoelastic Wall Rheology Applied to Arterial Dynamics
Validity of the Moens-Korteweg Equation
Time Domain Reflectometry in a Model of the Arterial System
New Approaches to Electromagnetic Measurement of Blood Flow and Vasomotion Without Recourse to Surgery
Control Theory and Regulation
Regulation of Blood Volume
Changes in Blood Flow-Distribution During the Application of Multiple Stresses
Optimality Principles Applied to the Design and Control Mechanisms of the Vascular System
Autonomic Vascular Responses in the Splanchnic Region
Response of Renal Blood Flow and Renal Sympathetic Nerve Activity to Baroreceptor and Emotional Stimuli in the Conscious Dog
Cerebral Blood Flow Regulation Under the Conditions of Arterial Hypoxia
Minimization of the External Work of the Left Ventricle and Optimization of Flow and Pressure Pulses
Cardiovascular Dynamics and Coronary Arteries
Influence of Arterial Impedance on Ventricular Function
The Effect of Systolic Rise in Arterial Pressure on Stroke Volume and Aortic Flow
Effect of Ventricular Pacing on Systolic Blood Pressure at Patients With Hypertension
Dependence of Peripheral Resistance on Heart Rate
Instantaneous Blood Flow Velocity Profiles After Aortic Valve Replacement
Fluid Mechanics of Natural Cardiac Valves
Early Mortality Due to Ventricular Fibrillation, and the Vulnerability of the Heart Following Acute Experimental Coronary Occlusion: Possible Mechanisms and Pharmacological Prophylaxis
Direct Nervous Effects on Coronary Flow in Conscious Dogs
Laudatio
Laudatio für Herrn Professor Dr. E. Wetterer.