The Carbonic Anhydrases: Current and Emerging Therapeutic Targets

The Carbonic Anhydrases: Current and Emerging Therapeutic Targets

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This volume assembles and integrates the wealth of diverse information that is now accumulating in this burgeoning field. The existing and potential therapeutic applications of targeting CA cover a remarkably wide-range of diseases and disorders and have generated increasing and extensive interest in recent years. Its inter-disciplinary approach embraces both the most up-to-date therapeutic application of CA-targeting and the latest research data that will provide a platform for the development of novel applications. The interested audience comprises scientists and clinicians from many relevant disciplines within science and medicine.



Dedication

Preface.-The carbonic anhydrases in health and disease
Carbonic anhydrase isozymes as diagnostic biomarkers and therapeutic targets
Targeting carbonic anhydrases in vascular and pulmonary disease
Carbonic anhydrase inhibitors in ophthalmology:  glaucoma and macular oedema
Targeting carbonic anhydrase isozymes in the treatment of neurological disorders
Potential of carbonic anhydrase inhibitors in the treatment of oxidative stress and diabetes
An overview of carbonic anhydrase-related neoplasms
The carbonic anhydrase IX interactome and the regulation of cancer progression
Carbonic anhydrase IX: current and emerging therapies
Carbonic anhydrase inhibitors: designing isozyme-specific inhibitors as therapeutic agents
Carbonic anhydrase inhibitors: identifying therapeutic cancer agents through virtual screening
Targeting carbonic anhydrase IX in tumour imaging and theranostic cancer therapy.


ISBN 978-3-030-79510-8
Artikelnummer 9783030795108
Medientyp Buch
Auflage 1st ed. 2021
Copyrightjahr 2021
Verlag Springer, Berlin
Umfang XII, 288 Seiten
Abbildungen XII, 288 p. 38 illus., 22 illus. in color.
Sprache Englisch