The Genetics and Development of Scoliosis
The Genetics and Development of Scoliosis
Our understanding of the genetic and developmental mechanisms underlying scoliosis is rapidly evolving, this timely second edition of The Genetics and Development of Scoliosis is to provide researchers, clinicians, and students with the most current views in this field.
This volume brings together leaders in understanding congenital and idiopathic scoliosis to present the current state of research, and to compare the genetic etiology of these conditions, in order to identify potential shared developmental mechanisms. This book will summarize the recent advances in studies of spinal development and how disruptions during embryogenesis in embryonic segmentation can lead to congenital vertebral defects. In addition, recent reports of genetic loci predisposing patients to develop juvenile and adolescent idiopathic scoliosis will be presented, and key clinical features are reviewed. Finally, there will be discussion of how genetic heterogeneity and gene-environment interactions may contribute to congenital scoliosis and isolated vertebral malformations.
Chapter1: Developmental and Functional Anatomy of the Spine
Chapter2: Environmental Factors and Axial Skeletal Dysmorphogenesis
Chapter3: Congenital Scoliosis and Segmentation Defects of the Vertebrae in the Genetic Clinic
Chapter4: The Genetics Contributing to Disorders involving Congenital Scoliosis
Chapter5: Animal Models of Idiopathic Scoliosis
Chapter6: Current Understanding of Genetic Factors in Idiopathic Scoliosis
Chapter7: Genetics and Functional Pathology of Idiopathic Scoliosis
Chapter8: Adolescence and Scoliosis: Deciphering the Complex Biology of Puberty and Scoliosis.
Kusumi, Kenro
Dunwoodie, Sally L.
| ISBN | 978-3-030-07944-4 |
|---|---|
| Artikelnummer | 9783030079444 |
| Medientyp | Buch |
| Auflage | 2. Aufl. |
| Copyrightjahr | 2019 |
| Verlag | Springer, Berlin |
| Umfang | XII, 199 Seiten |
| Abbildungen | XII, 199 p. 29 illus., 12 illus. in color. |
| Sprache | Englisch |
