On February 21 and 22, 1975, an International Workshop on the "Genetics of Diabetes Mellitus" was held in Göttingen, West-Germany. This workshop had been organized hy the Department of Medicine, University of Göttingen, and was generously sponsored by the Deutsche Forschungsgemeinschaft. Some forty geneticists and clinicians from Europe and N orth America, working in the field of diabetes both in man and laboratory animals, participated. The 25lectures presented at the workshop are now assembled for publication. Some of the animated discussion which followed the presentations has been included in the final papers by the speakers. Some lectures summarize the recent literature, others present data from recent research. Thus, a comprehensive and modem review of the theoretical and practical problems of diabetes are offered by this volume. related to the genetics The confusion about the mode of inheritance of diabetes mellitus during the last two decades can only be resolved by joint discussions between geneticists interested in diabetes and clinical diabetologists interested in genetics. Knowledge of modem genetics and of the heterogeneity of diabetes mellitus are necessary in order to disentangle the complex scene. Optimistically, the publication of this work on the genetics of diabetes will help to achieve this aim and to establish the concept of genetic heterogeneity of diabetes mellitus. The editors are grateful to Springer-Verlag, Heidelberg, for the prompt publication of these proceedings and to the Farbwerke Hoechst AG, Frankfurt (M), for their contribution to the printing costs.

1. Diabetes Mellitus - A Geneticist's Nightmare

2. The Genetics of Diabetes Mellitus - A Review of Family Data
3. The Genetics of Diabetes Mellitus - A Review of Twin Studies
4. Unsolved and Unsolvable Problems in Studying the Genetics of Diabetes
5. Clinician's View and Questions on the Genetics of Diabetes Mellitus
6. Etiological and Promoting Factors in the Pathogenesis of Diabetes Mellitus
7. Genetic Syndromes Associated with Glucose Intolerance
8. The Natural History of Idiopathic Diabetes Mellitus. Heterogeneity of Insulin Responses in Latent Diabetes
9. Genetic Heterogeneities within Idiopathic Diabetes
10. The Inheritance of Maturity-Onset Type Diabetes in Young People
11. A Possible Virus Etiology for Juvenile Diabetes
12. HLA, Autoimmunity and Insulin-Dependent Diabetes Mellitus
13. Environmental Factors and Genetic Interactions
14. Diabetes Mellitus and Impaired GlucoseTolerance in Diseases with Chromosomal Aberrations
15. Diabetes Mellitus and Hyperlipidemias
16. Genetic Syndromes Associated with Lipatrophic Diabetes
17. Hereditary Hyperglycemic Syndromes in Laboratory Rodents
18. Environmental Influences on the Manifestation of Diabetes Mellitus in Chinese Hamsters
19. Diabetes in the Offspring of Conjugal Diabetic Parents
20. Diabetes Mellitus in Identical Twins
21. Microangiopathy in Diabetics of Different Etiologies
22. Diabetic Complications in Concordant Identical Twins
23. Prospective Studies on Patients with Asymptomatic Diabetes
24. Problems in Genetic Counselling for Diabetes Mellitus
25. Towards a Better Understanding of the Genetic Basis of Diabetes Mellitus.