The Microbiome in Respiratory Disease
The Microbiome in Respiratory Disease
The book is organized into two main sections. Part I, Principles and Tools, covers conceptual modeling of the respiratory microbiome, experimental methodology with a focus on a priori considerations in study design and sampling, laboratory and computational methods for analysis of respiratory microbiome data, and minimizing interpretive pitfalls. Part II, Applications, discusses the evidence from specific studies that have shed novel insights into the influence of respiratory microbiota on mechanisms or outcomes in specific diseases. Based on current best evidence, disease-specific chapters include chronic rhinosinusitis, asthma (pediatric and adult studies), chronic obstructive pulmonary disease (COPD), cystic fibrosis (CF), bronchiectasis not due to CF, idiopathic pulmonary fibrosis, and lung transplant.
This is an ideal reference for forward-thinking practitioners with interest in novel developments in precision medicine applications in lung disease, as well as translational scientists in the field of microbiology, immunology and lung biology.
SECTION I: Principles and Tools of Respiratory Microbiome Investigation
Conceptual Framework and Hypothesis Testing
Study Design and Sampling Considerations
Laboratory Platforms to Study the Microbiome
Analysis and Reporting of Microbiome Data
SECTION II: Applications in the Study of Specific Diseases
Chronic Rhinosinusitis /Allergic Rhinitis
Bronchiolitis, Viral Infection and Pediatric Asthma Risk
Asthma Pheotype
Cystic Fibrosis
Bronchiectasis (non-CF)
COPD
Idiopathic Pulmonary Fibrosis
Lung Transplantation and Immune Suppression
The Future: Knowledge gaps and priorities.
Huang, Yvonne J.
Garantziotis, Stavros
ISBN | 978-3-030-87103-1 |
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Artikelnummer | 9783030871031 |
Medientyp | Buch |
Auflage | 1st ed. 2022 |
Copyrightjahr | 2021 |
Verlag | Springer, Berlin |
Umfang | XI, 305 Seiten |
Abbildungen | XI, 305 p. 16 illus. in color. |
Sprache | Englisch |