The Neuregulin-I/ErbB Signaling System in Development and Disease
The Neuregulin-I/ErbB Signaling System in Development and Disease
Neuregulins are EGF-like growth and differentiation factors that interact with tyrosine kinase receptors of the ErbB family. this signailing system has a wide range of functions during development of the nervous system, the heart, and the mammary gland. Furthermore, Neuregulin signals are also involved in the development of human diseases including breast cancer, heart disease and the pathogenesis of schizophrenia.
This monograph reviews the biology of Neuregulins and their receptors and summarizes recent research, which has established crucial functions of this signaling system during development and disease.
<p>Introduction - Molecular control of development
Biology of the Neuregulin/ErbB signaling networkNeuregulins and their receptors
Developmental functions of the Neuregulin-1/ErbB signalling pathway
Interacting molecules - the Sox10/ErbB connection
NRG-1/ErbB signals and disease
Abbreviations
References
Subject index</p>
Britsch, Stefan
| ISBN | 978-3-540-37105-2 |
|---|---|
| Artikelnummer | 9783540371052 |
| Medientyp | Buch |
| Copyrightjahr | 2007 |
| Verlag | Springer, Berlin |
| Umfang | XI, 70 Seiten |
| Abbildungen | XI, 70 p. |
| Sprache | Englisch |
