The Role of Natural Products in Drug Discovery

The Role of Natural Products in Drug Discovery

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Natural Products have been important sources of useful drugs from prehistoric times to the present. This book gives an overview about this field and provides important recent contributions to the discovery of new drugs generated by research on natural products.
Total synthesis of natural products with interesting biological activities is paving the way for the preparation of new and improved analogs. The methods of combinatorial chemistry permit the selection of the best drug from a large number of candidates. Beyond synthesis and evaluation of organic molecules a number of new bioorganic methods are coming to the fore and will be discucced in this isue of the ERnst schering Research Foundation workshop proceedings.

1 Synthesis of Immunomodulatory Marine Natural Products
2 The Pederin Family of Antitumor Agents: Structures, Synthesis and Biological Activity
3 Biotherapeutic Potential and Synthesis of Okadaic Acid
4 Total Synthesis of Marine Natural Products Driven by Novel Structure, Potent Biological Activity, and/or Synthetic Methodology
5 Total Synthesis of Antifungal Natural Products
6 Combinatorial Methods to Engineer Small Molecules for Functional Genomics
7 Natural Products in Drug Discovery
8 Tools for Drug Discovery: Natural-product-based Libraries
9 Genetic Selection as a Tool in Mechanistic Enzymology and Protein Design
10 The Biotechnological Exploitation of Medicinal Plants
11 Multifunctional Asymmetric Catalysis
12 New Directions in Immunopharmacotherapy
Previous Volumes Published in this Series.
ISBN 978-3-662-04044-7
Artikelnummer 9783662040447
Medientyp Buch
Auflage Softcover reprint of the original 1st ed. 2000
Copyrightjahr 2013
Verlag Springer, Berlin
Umfang XIII, 351 Seiten
Abbildungen XIII, 351 p.
Sprache Englisch