Bioinformatics is an interdisciplinary science which involves molecular bi- ogy, molecular chemistry, physics, mathematics, computational sciences, etc. Mostofthebooksonbiomathematicspublishedwithinthepasttenyearshave consistedofcollectionsofstandardbioinformaticsproblemsandinformational methods,andfocus mainly onthe logisticsofimplementing andmakinguse of various websites, databases, software packages and serving platforms. While these types of books do introduce some mathematical and computational methods alongside the software packages, they are lacking in a systematic and professional treatment of the mathematics behind these methods. It is signi?cant in the ?eld of bioinformatics that not only is the amount of data increasing exponentially, but collaboration is also both widening and deepening among biologists, chemists, physicists, mathematicians, and c- puter scientists. The sheer volume of problems and databases requires - searchers to continually develop software packages in order to process the huge amounts of data, utilizing the latest mathematical methods. The - tent of this book is to provide a professional and in-depth treatment of the mathematical topics necessary in the study of bioinformatics.

Outline

Outline
Mutations and Alignments
Stochastic Models of Mutations and Structural Analysis
Modulus Structure Theory
Super Pairwise Alignment
Multiple Sequence Alignment
Network Structures of Multiple Sequences Induced by Mutation
Alignment Space
Protein Configuration Analysis
Background Information Concerning the Properties of Proteins
Informational and Statistical Iterative Analysis of Protein Secondary Structure Prediction
Three-Dimensional Structure Analysis of the Protein Backbone and Side Chains
Alignment of Primary and Three-Dimensional Structures of Proteins
Depth Analysis of Protein Spatial Structure
Analysis of the Morphological Features of Protein Spatial Structure
Semantic Analysis for Protein Primary Structure.